Two surgical approaches for early-stage endometrial cancer treatment

This trial is testing two different surgical approaches for treating early-stage endometrial cancer using a newer, minimally invasive technique called v-NOTES (vaginal natural orifice transluminal endoscopic surgery). Instead of making large cuts, surgeons use the vagina as a natural pathway to reach and remove the uterus, ovaries, and sentinel lymph nodes—the lymph nodes most likely to contain cancer. The study compares two different ways of finding and removing these lymph nodes to see which approach works better and causes fewer complications.

Endometrial cancer is often treated with surgery, but traditional approaches can cause significant scarring and recovery complications. This newer surgical technique aims to reduce these risks, but doctors haven't yet standardized the best way to find and remove sentinel lymph nodes using this method. This study will help determine which of the two approaches is safer and more effective.