Plain-English translation of NCT06872645 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers want to understand how your body stores sodium when you're on peritoneal dialysis. This trial will test two different dialysis solutions — one with no sodium and one with the standard sodium content — to see if your body can store sodium in places beyond the usual fluid spaces. The goal is to help doctors better manage sodium and fluid balance in dialysis patients.
Doctors have long wondered whether the body stores sodium in hidden ways that aren't captured by standard measurements. Understanding this could help improve how dialysis treatments are designed and how well they help manage blood pressure and fluid balance in patients with kidney failure.
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You will stay in the hospital for two separate 5-day periods, with a 6-week break between them. During each stay, you'll receive your regular dialysis treatment using one of two different solutions — one time with a sodium-free solution and one time with standard dialysis fluid. The study team will carefully measure your sodium, fluid balance, weight, and blood pressure throughout to track how your body responds to each treatment.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
United States
Sponsor
Yale University
Collaborators
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Enrollment target
~10 participants
Started
October 2025
Primary completion
June 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Veena Rao, PhD
Yale University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.