Plain-English translation of NCT06877143 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether giving people with ALS extra calories through a feeding tube (PEG) can help them maintain their weight and energy better. Right now, doctors estimate calorie needs using general formulas, but this study measures each person's exact energy needs and then compares two groups: one receiving their full measured calorie requirement, and one receiving 20% more calories than that.
People with ALS often lose weight and struggle to maintain their energy, which can affect how quickly the disease progresses. This trial is investigating whether giving this treatment extra calories might help preserve body weight and energy levels better than standard nutrition alone.
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You would be randomly assigned to receive either your measured calorie requirement or 20% more calories through your PEG feeding tube. Your energy needs would be measured precisely using a non-invasive breathing test and a physical activity questionnaire. You would continue this nutrition plan alongside your regular ALS treatment, and the study team would monitor how your weight and energy levels change over time.
AI-generated summary from trial data · Jun 1, 2026 · Not medical advice
Germany
Sponsor
University of Ulm
Enrollment target
~76 participants
Started
March 2025
Primary completion
March 2031
Age range
18 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Christine Herrmann, Dr.
University of Ulm
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.