Plain-English translation of NCT06880679 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether ultrasound—a safe imaging tool that does not use radiation—can be used to diagnose acute chest syndrome, a serious lung complication that affects people with sickle cell disease. Currently, doctors use chest X-rays to identify this condition, but this study wants to see if ultrasound might work just as well while avoiding the radiation exposure.
Acute chest syndrome is a dangerous complication of sickle cell disease that causes fever, low oxygen levels, and breathing problems. While chest X-rays can diagnose it, they expose patients to radiation; researchers hope ultrasound could be an equally reliable alternative without that radiation risk.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will receive ultrasound scans on days 1, 3, and 5 of your hospitalization. These scans are painless, non-invasive, and use sound waves instead of radiation to create images of your lungs. The study team will use these ultrasound images to see if they can reliably detect acute chest syndrome, and compare the results with standard chest X-rays.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Indiana University
Enrollment target
~30 participants
Started
April 2025
Primary completion
June 2026
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Thomas Fisher-Heath, DO
Indiana University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.