Plain-English translation of NCT06880705 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a new support program called the TLC Program, designed specifically for transgender women who have experienced substance use concerns. The program is delivered online through group sessions led by peers who have lived experience as transgender women. Researchers believe that addressing stigma and helping people feel affirmed in their gender identity can reduce substance use and lower HIV risk.
Transgender women face higher rates of substance use and HIV compared to the general population, partly because stigma and lack of gender affirmation can push people toward unsafe situations. This study exists to test whether a supportive, affirming program can help reduce these risks by addressing the root causes—stigma and the need for recognition and support of gender identity.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be randomly placed into one of two groups. Both groups receive standard counseling about substance use and HIV prevention. The second group also participates in the TLC Program—an online peer-led group intervention where you'll connect with other transgender women in a supportive environment. The program focuses on reducing stigma, affirming your gender identity, and building skills to reduce substance use and HIV risk.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
United States