Plain-English translation of NCT06882850 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying whether low-dose aspirin can prevent a serious pregnancy condition called preeclampsia by changing how your immune system works during pregnancy. This medication is already used to help prevent this complication, but doctors want to understand exactly how it works. This small study will compare immune system changes in pregnant women who take the medication with those who don't need it.
Preeclampsia is a dangerous pregnancy complication that affects blood pressure and can harm both mother and baby. While this medication is sometimes given to prevent it, scientists don't fully understand the mechanism behind why it works—this study aims to fill that gap.
You likely qualify if…
You likely don't qualify if…
If you qualify and are in the high-risk group, you would take a daily low-dose aspirin tablet and have blood drawn at three points during your pregnancy (once in each trimester), usually during your regular prenatal visits. A comparison group of low-risk pregnant women would also have blood drawn at the same three time points, but would not take the medication. The study lasts the full length of your pregnancy, about 40 weeks.
AI-generated summary from trial data · Aug 22, 2026 · Not medical advice
Portugal
Sponsor
Unidade Local de Saúde de Coimbra, EPE
Enrollment target
~30 participants
Started
February 2024
Primary completion
March 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years and older
Sex
Female only
Last updated on clinicaltrials.gov in March 2025.
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Central contact
Ana L Areia, PhD, MD
University of Coimbra
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