Plain-English translation of NCT06886477 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a Mediterranean diet—a eating pattern rich in fruits, vegetables, whole grains, olive oil, and fish—can help reduce chronic pain in people with sickle cell disease. Researchers will provide prepared Mediterranean diet meals to some participants for 4 weeks, while others continue eating their usual diet, to see if this dietary approach makes a real difference in pain management.
People with sickle cell disease often experience chronic pain that is hard to treat with standard medications alone. This study explores whether changing what people eat might help ease this pain by reducing inflammation in the body.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will be randomly assigned to either receive prepared Mediterranean diet meals for 4 weeks or continue eating your usual diet at home. The study is designed as a crossover, meaning if you start in one group, you may later try the other approach. Throughout the study, you will likely complete surveys about your pain levels and dietary habits. The entire study lasts about 8 weeks.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
United States
Sponsor
University of Illinois at Chicago
Enrollment target
~30 participants
Started
May 2025
Primary completion
June 2026
Age range
18 Years and older
Last updated on clinicaltrials.gov in April 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Lisa Tussing-Humphreys, PhD, MS, RD
University of Illinois at Chicago
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.