Learn Data For Researchers Find trials matched to me

Learn Data For Researchers Find trials matched to me →

Clinical trial discovery in plain English. Data sourced from ClinicalTrials.gov.

About Privacy ClinicalTrials.gov ↗

Stella is not a medical provider and does not give medical advice. AI-generated summaries are for informational purposes only. Always consult your doctor before making any healthcare decisions.

Choose between daily pills or monthly injections to manage your HIV | stella

Back to Human Immunodeficiency Virus (HIV) Infection trials

Recruiting

Helping young people with HIV choose the best treatment option

Plain-English translation of NCT06886971 on ClinicalTrials.gov ↗ · Source last updated February 2026 · Translation generated June 2026 · How we translate trials

This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.

What is this trial?

The SAVVY Study is testing whether giving young people with HIV more choices about their treatment — specifically, offering cabotegravir and rilpivirine as a long-acting injection given every 4 to 8 weeks instead of daily pills — can help them stay healthy and keep their virus under control. Researchers know that young people often struggle with taking daily medications, so this study gives them the chance to pick the treatment that works best for their life.

Young people with HIV often have a harder time taking their medications consistently and staying healthy compared to older adults. This study exists to remove barriers and give young people real choices about their treatment, so they can pick an option that fits their lifestyle and helps them succeed.

Do you qualify?

You likely qualify if…

you are between 12 and 30 years old
you have been prescribed HIV treatment (antiretroviral therapy)
you are willing to sign a consent form and talk with your HIV care provider about the study

You likely don't qualify if…

you have certain drug-resistant strains of HIV that would not respond to this medication
you are pregnant
you have significant mental health or cognitive concerns that would make it hard to participate, in your doctor's opinion
you are currently very ill or hospitalized
you plan to move away within the next 12 months

What participation looks like

You'll start by meeting with a counselor to discuss whether you'd prefer to stay on daily pills or try the monthly injection—whichever is right for you. If you're interested in the injection, the study team will help with paperwork and logistics to get you access. Over 12 months, you'll come in for check-in visits at 3, 6, 9, and 12 months where your doctor will check your viral load and ask about your quality of life and how you're doing on your chosen treatment.

AI-generated summary from trial data · Jun 17, 2026 · Not medical advice

Trial locations(1 site)

United States

Johns Hopkins University, Baltimore, Maryland

Key details

Sponsor

Johns Hopkins University

Collaborators

National Institute of Mental Health (NIMH)

Enrollment target

~288 participants

Started

November 2024

Primary completion

November 2027

Age range

12 Years – 30 Years

Last updated on clinicaltrials.gov in February 2026.

Contact the research team directly

Reach out to the team running this trial. Response times vary — some teams are faster than others.

Central contact

Allison Agwu, MD, SCM

Johns Hopkins University

Interested in joining?

Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.

Follow this trial

Get notified in plain English when this trial's status changes. No account required.

View full record on ClinicalTrials.gov