Plain-English translation of NCT06888726 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a treatment called high-intensity transcranial alternating current stimulation (Hi-tACS)—a non-invasive procedure that delivers mild electrical currents to the brain through electrodes placed on your scalp. The goal is to see whether this treatment can help reduce negative symptoms of schizophrenia, such as withdrawal, lack of motivation, and difficulty with emotions, in people who are already taking antipsychotic medication.
Many people with schizophrenia continue to struggle with negative symptoms even when their medication works well for other aspects of the illness. Researchers want to know if this treatment can help improve these lingering symptoms and help patients feel more engaged with life and relationships.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would be randomly assigned to either receive the full brain stimulation treatment or a placebo (sham) version. You would visit the clinic twice a day, Monday through Friday, for two weeks—that's 20 sessions total. Each session lasts 40 minutes and involves placing electrodes on your scalp to deliver gentle electrical currents. You would continue taking your regular schizophrenia medication throughout. The researchers would assess your symptoms, thinking skills, social functioning, and quality of life at the start, after two weeks, and again at three months.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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