Plain-English translation of NCT06890650 on ClinicalTrials.gov ↗ ·
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether fecal microbiota transplantation (FMT)—a procedure where healthy stool from a donor is placed into your colon—can help treat newly diagnosed Crohn's disease. The study also tests a special diet designed to reduce inflammation in the gut, either alone or combined with the transplant procedure. Researchers want to see if these approaches, along with standard medical care, can help bring your disease under control.
Crohn's disease involves problems with the bacteria and microbes in your gut that contribute to inflammation and symptoms. This trial is exploring whether restoring healthy gut bacteria through transplants and dietary changes might offer a new way to control the disease in patients who haven't yet received other advanced treatments.
You likely qualify if…
You likely don't qualify if…
You will be randomly assigned to receive one of four combinations: fecal transplants with the special diet, fecal transplants with general dietary advice, the special diet with mock transplants, or mock transplants with general advice. If you receive transplants, you'll have colonoscopy procedures at weeks 0, 2, and 6, followed by maintenance procedures every 8 weeks if your disease improves. Throughout the 48-week study, you'll attend clinic visits, have blood and stool tests, and if assigned to the special diet, you'll meet with a dietitian and use an app to track your eating.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
India