Plain-English translation of NCT06891755 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our COPD research guide →This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing a new treatment called Apreo implants for people with severe emphysema — a type of lung damage where air gets trapped and makes breathing difficult. About half of participants will receive the implants (placed through a single breathing tube procedure) along with standard breathing medications and rehabilitation, while the other half will receive standard care alone. The study will follow participants for up to 3 years to see if the implants help them breathe better and improve their quality of life.
Emphysema causes permanent damage to tiny air sacs in the lungs, trapping stale air inside and making it hard to breathe in fresh air. Standard medications alone don't always help enough, so researchers are testing whether these implants can create a pathway for trapped air to escape, giving the lungs more room to work properly.
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If you qualify and are chosen for the treatment group, you will undergo one procedure where doctors pass a thin breathing tube down your windpipe and place up to 3 small implants in each lung in areas of severe damage. All participants receive standard medical care including medications, vaccinations, and breathing rehabilitation. You will visit the clinic at 1, 3, and 6 months, then at 1, 2, and 3 years after your procedure to check how you're doing, answer questions about your breathing and quality of life, and ensure no side effects have developed.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States