Plain-English translation of NCT06895798 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This completed research study examined how different surgical techniques used during major liver surgery affected the risk of heart injury in the days after surgery. Researchers looked at two different methods surgeons use to control blood flow to the liver during these long operations — one called Pringle occlusion and another called portal vein occlusion — to see if one method was safer for the heart than the other. The study included nearly 1,300 older patients or those with heart disease risks who underwent these types of surgeries.
During major liver surgery, surgeons sometimes need to temporarily stop blood flow to the liver to prevent excessive bleeding. However, this pause in blood flow and the return of blood afterward can stress the heart and cause injury, especially in older patients or those already at risk for heart problems. This study was designed to help doctors understand which surgical technique is safer for the heart.
Participants in this study had already undergone their liver surgery as part of routine clinical care; researchers then collected their medical records and followed their progress for up to one year after surgery. Some participants also had blood and liver tissue samples taken during or after surgery to help researchers understand how the different surgical techniques affected the body. The study tracked how often patients experienced heart injury within three days after surgery, how long they stayed in the hospital, and whether they had any complications within 30 days.
AI-generated summary from trial data · Jun 14, 2026 · Not medical advice
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