Plain-English translation of NCT06896682 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
After weight loss surgery, some patients experience sudden, dangerous drops in blood sugar called reactive hypoglycemia. This study is exploring whether changes in how the body produces and uses cortisol (a natural stress hormone) might be connected to these blood sugar crashes. Researchers will test your cortisol levels and monitor your blood sugar to understand this connection better.
Reactive hypoglycemia is a serious complication that affects quality of life for some people after weight loss surgery, but doctors don't fully understand what causes it. This research aims to identify whether cortisol metabolism changes are responsible, which could eventually lead to better treatments or prevention strategies.
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You will have two visits about 10 days apart. At your first visit, you'll provide blood samples, undergo a hormone stimulation test, and receive a small glucose monitor to wear on your skin for 10 days that continuously measures your blood sugar. You'll also collect urine samples and saliva samples at home. At your second visit, you'll drink a standardized meal, have more blood samples taken every 30 minutes over 3 hours while wearing the glucose monitor, and complete questionnaires about any low blood sugar symptoms you experienced. Total time commitment is about 5 hours across both visits.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
Denmark
Sponsor
Esbjerg Hospital - University Hospital of Southern Denmark
Enrollment target
~100 participants
Started
July 2025
Primary completion
December 2026
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Charlotte R Stolberg, MD PhD
Esbjerg Hospital - University Hospital of Southern Denmark
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.