Plain-English translation of NCT06904196 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether — a daily medication — works better when combined with a radiation procedure called SIRT (Selective Internal Radiation Therapy) compared to taking the medication alone. The study focuses on people whose liver cancer didn't respond to a previous treatment called TACE. Researchers want to see if adding the radiation procedure helps patients live longer and see their tumors shrink.
Some people with advanced liver cancer stop responding to standard treatments, and doctors need better options to help them. This trial is exploring whether combining this medication with a targeted radiation approach might give patients a better chance of controlling their cancer.
You likely qualify if…
You likely don't qualify if…
If you are assigned to the combined treatment group, you will first receive the radiation procedure (SIRT), and then begin taking the daily medication about a week later. If you are in the medication-only group, you will take the daily pill based on your body weight. You will continue treatment until your cancer progresses, you experience side effects you cannot tolerate, or your doctor decides to stop — whichever comes first. The study will monitor your response to treatment through scans and blood tests, and follow your health and survival over time.
AI-generated summary from trial data · Jul 8, 2026 · Not medical advice
China
Phase
Testing effectiveness
Sponsor
Second Affiliated Hospital of Guangzhou Medical University
Enrollment target
~78 participants
Started
April 2025
Primary completion
March 2028
Age range
18 Years – 75 Years
Last updated on clinicaltrials.gov in April 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mingyue Cai, Dr.
Second Affiliated Hospital of Guangzhou Medical University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.