Plain-English translation of NCT06904365 on ClinicalTrials.gov โ ยท Source last updated ยท Translation generated ยท How we translate trials
This trial is testing whether advanced imaging can help doctors safely deliver radiation to treat pelvic cancers โ like uterine, rectal, or cervical cancer โ while minimizing damage to the ovaries. Young women treated for these cancers often face premature ovarian failure, which can cause serious health problems. This study uses special imaging scans to map the ovaries' exact location, so doctors can adjust the radiation plan to spare them.
Many young women diagnosed with pelvic cancers need radiation therapy, but this treatment can permanently damage the ovaries and trigger early menopause, leading to heart problems, bone loss, sexual dysfunction, and emotional distress. Current ways to protect ovaries โ like surgery to move them โ don't always work or aren't available to everyone. This trial aims to find a simpler, more effective way to shield ovarian function.
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If you enroll, you will receive your standard cancer radiation treatment as planned. In addition, you will undergo special imaging scans of your pelvis using an advanced imaging machine called a HyperSight CBCT. You may have 1 to 10 total imaging scans across 1 to 5 separate imaging sessions โ typically just 2 scans about 10 minutes apart per session. These scans help doctors precisely locate your ovaries so they can customize your radiation plan to protect them. The entire study involves imaging only and does not change your cancer treatment.
AI-generated summary from trial data ยท Sep 3, 2026 ยท Not medical advice
United States