Plain-English translation of NCT06905262 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Researchers are studying the bacteria that live in your gut, mouth, and tumor to understand how they might be connected to liver cancer and how your immune system responds to it. This is not testing a specific medication, but rather collecting biological samples and analyzing them to discover new ways to fight cancer with immunotherapy — treatments that help your own immune system recognize and attack cancer cells.
Scientists have discovered that the bacteria living in your body may play a role in how cancer develops and how well your immune system can fight it. This study aims to find new targets for cancer vaccines and immunotherapies by mapping these bacterial connections, which could lead to better treatments in the future.
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If you enroll, you will be asked to provide samples including tissue (if available from previous biopsies), blood, saliva, and possibly stool samples. Researchers will analyze the bacteria and genetic material in these samples to identify patterns that might help develop new cancer treatments. The study does not involve taking medications — it is purely observational, focused on understanding your microbiome (the bacteria living in your body) and how it relates to your cancer.
AI-generated summary from trial data · Jul 20, 2026 · Not medical advice
Italy
Sponsor
National Cancer Institute, Naples
Enrollment target
~70 participants
Started
January 2023
Primary completion
September 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 100 Years
Last updated on clinicaltrials.gov in April 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Luigi Buonaguro, DR
IRCCS I.N.T. "G. Pascale"
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.