Testing a new medication combined with chemotherapy for gynecological cancers

This trial is testing a medication called relacorilant to see if it works better when combined with chemotherapy drugs like nab-paclitaxel and bevacizumab in patients with gynecological cancers—including ovarian cancer, endometrial cancer, and related cancers. The study has different treatment groups depending on your cancer type and history. Researchers want to understand whether adding this medication to existing cancer treatments can improve outcomes and help more patients.

Many patients with these gynecological cancers either stop responding to standard treatments or face treatment challenges after their cancer returns. This medication works through a different mechanism than typical chemotherapy, and researchers believe combining it with chemotherapy may help overcome treatment resistance and improve survival.