Plain-English translation of NCT06916208 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing capsinoid, a natural compound found in sweet peppers and chili peppers, to see if it can help activate brown adipose tissue—a special type of fat that burns calories to produce heat instead of storing energy. The study will enroll 38 obese teenagers and combine the medication with diet and exercise guidance over 4 weeks. Researchers believe this supplement, combined with healthy lifestyle changes, may help boost the body's natural calorie-burning ability.
Brown adipose tissue has been shown to help fight obesity by burning calories, but this tissue naturally decreases as children grow into adolescence. Scientists want to see if this medication can reactivate that calorie-burning tissue and help teenagers with obesity lose weight more effectively.
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You would take capsules three times daily for 4 weeks as part of a structured program that includes dietary guidance and exercise support. Half of participants will receive the active supplement from peppers, while the other half will receive capsules that look and taste identical but contain no active ingredient—neither you nor the researchers will know which group you're in. The study will likely include visits to measure your health and body composition before and after the 4-week program.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
France