Plain-English translation of NCT06917963 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
After certain types of bowel surgery, some patients experience excessive fluid drainage from their surgical opening (called a stoma), which can cause serious complications like dehydration and electrolyte imbalances. This trial tests whether omeprazole, a medication that reduces stomach acid, given at higher doses than usual can help decrease this fluid loss and improve patient outcomes compared to standard dosing.
Current standard treatments for excessive stoma drainage don't work well enough for many patients, leaving them at risk for serious complications and extended hospital stays. Early research suggests this medication might help by reducing the amount of fluid produced in the intestines, but doctors need to test whether higher doses work better.
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You will be randomly assigned to receive either the standard dose or a higher dose of the medication. The higher-dose group receives an initial larger dose followed by twice-daily doses during and after your hospital stay for a total of 10 days, while the standard group receives a single daily dose during hospitalization. You will have your stoma output carefully measured throughout the study to see if the higher dose helps reduce fluid loss and improves your recovery.
AI-generated summary from trial data · Jun 18, 2026 · Not medical advice
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