Plain-English translation of NCT06919614 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether adding regular sexually transmitted infection (STI) screening to HIV prevention care helps pregnant women stick with taking PrEP — a daily medication that prevents HIV infection. Researchers are enrolling 600 pregnant women without HIV in Botswana to see if this combined approach improves how often women take the medication and whether they continue using it after giving birth.
Many pregnant women who start HIV prevention medication stop taking it or don't use it consistently. Researchers believe that combining this medication with regular STI testing and treatment might help women stay more engaged with their care and continue protecting themselves throughout pregnancy and after delivery.
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If you join this study, you'll be randomly assigned to one of two groups. One group will receive regular STI testing (at enrollment, around 32 weeks of pregnancy, and 9 months after delivery), while the standard care group receives STI testing only at the 9-month visit. All participants will be offered PrEP and can choose between daily pills or an injection, and can change their method or stop at any time. You'll have follow-up visits for up to 9 months after your baby is born, during which the study team will check on your health, your baby's health, and how well you're taking the medication using a simple hair test.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
Botswana