Plain-English translation of NCT06921317 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing a new gene therapy called GVB-2001, delivered as a single injection directly into the front of your eye. The study wants to see if this treatment can safely lower eye pressure in people with primary open-angle glaucoma (a type of glaucoma where pressure inside the eye is too high). Researchers will enroll a small group of patients to carefully monitor how safe the treatment is and how well it works.
Primary open-angle glaucoma can lead to blindness if eye pressure stays too high, and some patients don't get enough relief from eye drops or other current treatments. This trial is exploring whether this new medication approach could offer a different way to control eye pressure and potentially prevent vision loss.
You likely qualify if…
You likely don't qualify if…
If you qualify, you will receive a single injection of the treatment into the front of your eye during a visit at the research center. The study is divided into two groups based on your vision and eye pressure levels, and researchers will carefully monitor your safety and how your eye responds over time. You will need to return for follow-up visits and eye exams throughout the study, with extended monitoring for at least one year after your injection.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China