Plain-English translation of NCT06922318 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing whether a new medication called works better when combined with other drugs to slow the growth of advanced prostate cancer. The trial uses a two-step approach: first, you would take along with testosterone injections, and if your cancer progresses, you would then switch to taking with a different drug called . The goal is to see if this sequential strategy helps keep cancer from growing longer than standard treatments alone.
Many men with advanced prostate cancer eventually develop resistance to the current standard medications, meaning those drugs stop working. This trial is exploring whether combining this new medication with different treatment approaches at different stages might help patients live longer without their cancer getting worse.
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You would enter the trial taking the first medication combination: daily pills of plus one testosterone injection on the first day of each 28-day cycle. You would continue this for as long as your scans show your cancer is stable. Once your cancer starts progressing again on imaging, you would switch to the second phase, taking two different medications daily (the higher dose of and ). Throughout the study, you would continue your hormone suppression therapy and have regular blood tests and imaging scans to monitor your response.
AI-generated summary from trial data · Jun 22, 2026 · Not medical advice
United States