Plain-English translation of NCT06925061 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This trial is testing a medication called EXL01 to see if it can help prevent Crohn's disease from returning after surgery. About 80 people who have recently had bowel surgery for Crohn's disease will take either the medication or a placebo (a dummy pill) for 6 months. Researchers will check how well the treatment works and track any side effects.
After surgery for Crohn's disease, the condition often comes back in the remaining bowel. This study is exploring whether this new treatment might help prevent that recurrence and give patients a better quality of life after their operation.
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You would take a daily oral dose of either the medication or placebo for up to 6 months while your doctor monitors your recovery. During this time, you'll have regular clinic visits where doctors will do endoscopy (a camera test to look inside your bowel) to check for signs of disease returning, and you'll provide blood and stool samples for testing. If you experience a disease flare-up before 6 months, you'll stop taking the study medication and have a final check-up, and you'll be monitored for safety for 4 weeks after stopping.
AI-generated summary from trial data · Jun 5, 2026 · Not medical advice
France