Plain-English translation of NCT06925893 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing a new medical device that delivers lutein—a natural nutrient found in food—directly into your eye using a gentle electrical method called iontophoresis. Lutein is known to protect the retina and may slow the progression of age-related macular degeneration (AMD), a condition that affects vision as we age. This device aims to get lutein to the back of your eye more effectively than taking pills by mouth, which many patients find inconvenient or ineffective.
While oral lutein supplements have been shown to help prevent AMD from getting worse, many patients struggle to take daily pills for years. This new treatment offers a faster, more direct way to deliver lutein to the eye in high doses within hours rather than months, and may be easier for patients to stick with over time.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would receive treatments using the lutein iontophoresis device at the research clinic. The device uses a small applicator placed against the white of your eye and gentle electrical pulses to deliver lutein directly into your eye tissue—a quick, painless procedure. You would need to attend follow-up visits so doctors can monitor how well the treatment works and check for any side effects.
AI-generated summary from trial data · Jun 12, 2026 · Not medical advice
Italy
Federico II University
Enrollment target
~80 participants
Started
November 2024
Primary completion
December 2024
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
55 Years – 100 Years
Last updated on clinicaltrials.gov in April 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Ciro Costagliola, Director Of Ophthalmology Unit
Federico II University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.