Plain-English translation of NCT06928506 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a treatment called Hi-OxSR—a form of oxygen therapy administered through inhalation—to help people who are struggling with lingering symptoms months after their COVID-19 infection. Researchers want to find out whether using this oxygen therapy for 30 minutes twice a day, at different oxygen levels and durations, can improve symptoms like brain fog, fatigue, and other long-COVID effects. This is part of a larger research effort called RECLAIM, which is exploring different approaches to help people recover from post-COVID condition.
Many people continue to experience debilitating symptoms—such as cognitive problems, fatigue, and shortness of breath—long after their initial COVID infection has cleared. Current standard treatments don't work well enough for everyone, so researchers are testing whether this oxygen therapy might offer relief for those still struggling with these lingering effects.
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If you join this study, you'll use the oxygen therapy device at home for 30 minutes twice a day over either 2 or 4 weeks, depending on which group you're randomly assigned to. Different groups will receive different oxygen levels to help researchers figure out which approach works best. You'll need to attend study visits for screening, monitoring, and follow-up assessments to measure whether your symptoms improve.
AI-generated summary from trial data · Jun 15, 2026 · Not medical advice
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