Plain-English translation of NCT06929442 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether a four-week training program called Resilience Training can help young adults who are experiencing psychotic symptoms—like unusual thoughts or perceptions—stay mentally healthy and prevent serious mental illness from developing. The program teaches three main skills: mindfulness (focusing your attention), self-compassion (being kind to yourself), and mentalization (understanding your own thoughts and feelings). Researchers will compare this to a control group that learns practical life skills instead.
Young adults who have early psychotic experiences are at risk of developing serious mental health conditions, but most prevention programs have not been specifically designed for this group. This trial aims to see whether teaching emotional regulation and self-awareness skills can reduce symptoms and help students stay in school and succeed academically.
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If you are chosen for this study, you will attend four weekly sessions lasting 90 minutes each. You will be randomly assigned to either the Resilience Training group (learning mindfulness, self-compassion, and emotional understanding skills) or the Life Skills Training group (learning practical skills like financial planning and safety). Throughout and after the program, researchers will check in with you to see how you are doing mentally and academically, and you may be asked to complete some tests or brain imaging scans to help scientists understand how the training works.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
United States
Sponsor
Massachusetts General Hospital
Enrollment target
~192 participants
Started
February 2025
Primary completion
December 2028
Age range
18 Years – 30 Years
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Daphne J Holt, MD, PhD
Massachusetts General Hospital
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.