Plain-English translation of NCT06934889 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Glioblastoma research guide →Phase 1 — Testing in a small group (usually 20–80 people) to find a safe dose and watch for side effects.
This trial is testing whether two new medications called or , when combined with an existing treatment called , can help people with glioblastoma. Glioblastoma is an aggressive brain cancer, and this study wants to see if these medication combinations work better when added to standard treatments like surgery, radiation, and chemotherapy.
Glioblastoma is a very serious brain cancer that often returns or stops responding to standard treatments. Researchers hope that by adding these new medications to existing treatments, they can help patients live longer and have better outcomes.
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Depending on your situation, you will either receive the new medication before and after brain surgery (if your cancer has returned) or receive the medication alongside standard radiation and chemotherapy (if you are newly diagnosed). The study has two stages: Stage 1 tests safety and tolerability, and if successful, Stage 2 will expand the research. You will need regular MRI scans, blood tests, and clinic visits to monitor how you're tolerating treatment and how your tumor is responding.
AI-generated summary from trial data · Aug 29, 2026 · Not medical advice
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