Plain-English translation of NCT06935305 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing whether a newer, faster laboratory method called OSNA works just as well as the traditional method (ultrastaging) at finding cancer cells in lymph nodes that are removed during endometrial cancer surgery. Both methods examine the same lymph nodes to look for signs that cancer has spread, but they use different laboratory techniques to do so.
Doctors need reliable ways to check if endometrial cancer has spread to the lymph nodes, because this information helps guide treatment decisions and predict outcomes. This trial will determine whether the newer OSNA method can replace the standard method, potentially offering faster results and better care for patients.
You likely qualify if…
You likely don't qualify if…
If you join this study, you will have surgery as planned for your endometrial cancer. The difference is that your removed lymph nodes will be tested using one of two methods—either the standard ultrastaging approach or the newer OSNA method—assigned randomly. The study will follow about 1,922 patients across multiple hospitals to compare how well each method detects cancer in the lymph nodes.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
Italy
Sponsor
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Collaborators
Sysmex Europe GmbH
Enrollment target
~1,922 participants
Started
July 2025
Primary completion
September 2026
Sex
Female only
Last updated on clinicaltrials.gov in November 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Francesco Fanfani, Professor
Fondazione Policlinico Agostino Gemelli IRCCS
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.