A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart — Stella
Home / Heart Failure / A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart View on ClinicalTrials.gov Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.
(638 sites) United States
Alliance for Multispecialty Research, LLC, Mobile, Alabama Drug Research and Analysis Corporation, Montgomery, Alabama Cure Clinical Research, Beverly Hills, California Valley Clinical Trials, Inc., Covina, California North Coast Cardiology, Encinitas, California Orange County Research Center, Lake Forest, California Merced Vein and Vascular Center, Merced, California Radin Cardiovascular Medical Group, Newport Beach, California Amicis Research Center - Nordhoff, Northridge, California University of California San Diego, San Diego, California Paradigm Clinical Research - San Diego, San Diego, California Amicis Research Corporate, Santa Clarita, California Care Access Research, Thousand Oaks, California Bridgeport Hospital, Bridgeport, Connecticut Bay Area Cardiology, Brandon, Florida Cardiology Associates Research Co., Daytona Beach, Florida Suncoast Research Associates, LLC, Doral, Florida Malcom Randall VA Medical Center, Gainesville, Florida Velocity Clinical Research-Hallandale Beach-67888, Hallandale, Florida University of Florida, Jacksonville, Florida East Coast Institute For Research, LLC, Jacksonville, Florida First Coast Cardiovascular Institute, Jacksonville, Florida Jacksonville Center for Clinical Research, Jacksonville, Florida University of Miami - Miller School of Medicine, Miami, Florida Infinite Clinical Research Inc, Miami, Florida Inpatient Research Clinic, LLC, Miami Lakes, Florida Innovation Medical Research Center, Palmetto Bay, Florida Peace River Cardiovascular Center, Port Charlotte, Florida St. Johns Center for Clinical Research, Saint Augustine, Florida Cardiology Partners Clinical Research Institute, Wellington, Florida Cozy Research LLC, Wesley Chapel, Florida Clinical Site Partners, LLC, Winter Park, Florida Atlanta Clinical Research Centers, Atlanta, Georgia Columbus Regional Research Institute, Columbus, Georgia NSC Research Inc, Johns Creek, Georgia Northwest Heart Clinical Research, LLC, Arlington Heights, Illinois Illinois Masonic Hospital, Chicago, Illinois Chicago Medical Research, Hazel Crest, Illinois Clinical Investigation Specialists, Inc., Libertyville, Illinois AMR Park Ridge, Park Ridge, Illinois Springfield Clinic, Springfield, Illinois Midwest Cardiovascular Research and Education Foundation, Elkhart, Indiana St. Francis Medical Group-Indiana Heart Physicians, Inc, Indianapolis, Indiana Indiana Medical Research Institute, Merrillville, Indiana Cardiovascular Research of Northwest Indiana, LLC, Munster, Indiana Reid Hospital, Richmond, Indiana The Iowa Clinic, PC, West Des Moines, Iowa University of Kansas Medical Center, Kansas City, Kansas Kansas Nephrology Research Institute, LLC, Wichita, Kansas Robert J Dole Veterans Affairs Medical Center, Wichita, Kansas West Houston Area Clinical Trial Consultants, LLC, Wichita, Kansas Norton Healtcare - Norton Heart and Vascular Institute, Louisville, Kentucky Heart Clinic of Hammond, Hammond, Louisiana Grace Research, LLC-Shreveport-64616, Shreveport, Louisiana Ascension Saint Agnes Heart Care, Baltimore, Maryland Metropolitan Cardiovascular Consultants, Beltsville, Maryland Capitol Cardiology Associates, Lanham, Maryland McLaren Bay Region Medical Center, Bay City, Michigan Cardiology and Vascular Associates - CAVA, Bloomfield Hills, Michigan Michigan Healthcare Professionals Pulse Cardiology, Farmington Hills, Michigan St. John Providence Hospital, Novi, Michigan Michigan Heart, PC, Ypsilanti, Michigan Minneapolis VA Health Care System, Minneapolis, Minnesota Mayo Clinic, Rochester, Rochester, Minnesota Regions Hospital, Saint Paul, Minnesota Jackson Heart Clinic, P.A., Jackson, Mississippi North Kansas City Hospital, Kansas City, Missouri Kansas City VA Medical Center, Kansas City, Missouri St. Louis Heart and Vascular, P.C., St Louis, Missouri Be Well Clinical Studies, Omaha, Nebraska Advanced Heart Care, LLC, Bridgewater, New Jersey Garden State Heart Care, PC, Manalapan, New Jersey Bassett Medical Center, Cooperstown, New York Mount Sinai Hospital-New York-52529, New York, New York Icahn School of Medicine at Mount Sinai, New York, New York IMA Clinical Research Lenoir, Lenoir, North Carolina Pinehurst Medical Clinic, Inc. - East, Pinehurst, North Carolina WakeMed, Raleigh, North Carolina Piedmont Healthcare, Inc., Statesville, North Carolina Wilmington Health, Wilmington, North Carolina VA Northeast Ohio Healthcare System, Cleveland, Ohio K and R Research LLC, Marion, Ohio Cardiology Consultants of Philadelphia, Yardley, Pennsylvania Bon Secours Medical Group Greenville Specialty Care, LLC, Greenville, South Carolina Monument Health, Rapid City, South Dakota Pharmatex Research, Amarillo, Texas Amarillo Heart Clinical Research Institute, Incorporated, Amarillo, Texas NextStage Clinical Research, Beaumont, Texas Headlands Research Brownsville, Brownsville, Texas Texas Health Research and Education Institute, Dallas, Texas Southwest Family Medicine Associates, Dallas, Texas Helios CR Inc - Fort Worth, Fort Worth, Texas The Methodist Hospital Research Institute, Houston, Texas DM Clinical Research Dallas, Irving, Texas DCOL Center for Clinical Research, Longview, Texas DCOL Center for Clinical Research, Longview, Texas North Texas Research Associates, McKinney, Texas Revival Research Institute, LLC - McKinney, McKinney, Texas Texas Institute Of Cardiology, McKinney, Texas Stryde Research, Plano, Texas Accurate Clinical Research, Inc., Richmond, Texas Baylor Scott and White Health, Temple, Texas Northwest Heart Center, Tomball, Texas NextStage Clinical Research, Waco, Texas Virginia Heart - Falls Church, Falls Church, Virginia Carient Heart and Vascular, Manassas, Virginia Sentara Norfolk General Hospital, Norfolk, Virginia Carilion Clinic, Roanoke, Virginia Argentina
Inst de Inv Clinicas-Bahia Blanca, Bahía Blanca Hospital Regional de Bahia Blanca, Bahía Blanca Centro de Investigaciones Metabolicas (CINME)-C.A.B.A-61553, C.a.b.a Hospital Italiano de Buenos Aires, Ciudad Autonoma Buenos Aires Fundacion Favaloro, Ciudad Autonoma Buenos Aires Mautalen- Salud e Investigacion, Ciudad Autonoma Buenos Aires Centro Medico Dra Laura Maffei, Ciudad Autonoma Buenos Aires Glenny Corp. S.A. Bioclinica Argentina, Ciudad Autonoma Buenos Aires Clinica Coronel Suárez, Coronel Suárez Sanatorio Allende, Córdoba Sanatorio Privado Duarte Quiros De Clinica Colombo SA, Córdoba
Belgium
AZ Sint-Blasius, Dendermonde Ziekenhuis Oost-Limburg, Genk Grand Hôpital de Charleroi, Gilly C.H.U. de Tivoli, La Louvière CHR de la Citadelle, Liège Brazil
Hospital Sirio Libanes, Bela Vista Hospital Felicio Rocho, Belo Horizonte Cardresearch Cardiologia Assistencial e de Pesquisas Ltda, Belo Horizonte L2IP -Instituto de Pesquisas Clínicas Ltda., Brasília Hospital DF Star, Brasília CECAP - Centro de Cardiologia Clínica, Brasília Hospital Angelina Caron, Campina Grande do Sul IPECC - Instituto de Pesquisa Clínica de Campinas, Campinas Hospital PUC-Campinas, Campinas I9 Pesquisas Clinicas - Loema Instituto de Pesquisa Clínica e Consultores SS Ltda, Campinas Hospital do Rocio, Campo Largo Fundacao Universidade de Caxias do Sul, Caxias do Sul PUC Trials - Núcleo de Pesquisa Clínica da Escola de Medicina da PUC-PR, Curitiba
Bulgaria
Medical center 4LIFE Ltd., Burgas MHAT Heart and brain, Burgas Medical Center Doktor Staykov Ltd., Burgas Diamedical Medical Center 2013, Dimitrovgrad MHAT "Sveta Ekaterina-Dimitrovgrad", EOOD, Dimitrovgrad Medical Center New Polyclinic Gabrovo Ltd., Gabrovo MHAT Ivan Skenderov EOOD, Gotse Delchev Medical Center Rodopimed EOOD, Kardzhali Medical Center Hera - Kyustendil EOOD, Kyustendil Tonus 2013 Ltd., Pazardzhik Ambulatory Individual Practice for Cardiology Specialized Medical Care, Pernik Medical Center Medconsult Pleven OOD, Pleven MHAT Heart and brain, Pleven Canada
Saul Vizel Medicine Professional Corporation, Cambridge, Ontario Health Sciences North, Greater Sudbury, Ontario Elevate Clinical Research - KMH Hamilton, Kitchener, Ontario KMH Cardiology Centres (Mississauga), Mississauga, Ontario Oakville Trafalgar Memorial Hospital, Oakville, Ontario James Cha, MD, Oshawa, Ontario Kawartha Cardiology Clinical Trials, Peterborough, Ontario CardioQuest Research Centre, Sarnia, Ontario Niagara Health System - St. Catharines Site, St. Catharines, Ontario Fadia El Boreky Medicine Professional Corporation, Waterloo, Ontario ViaCar Recherches Cliniques Inc. (Brossard), Brossard, Quebec Diex Recherche (Sherbrooke), Sherbrooke, Quebec Diex Recherche (Trois-Rivieres), Trois-Rivières, Quebec Chile
CeCim - Centro de Estudios Clinicos e Investigacion Medica, Santiago Centro de Investigación del Maule, Talca Hospital Las Higueras, Talcahuano CINVEC - Centro de Investigacion Clinica V Reg.,Vina del Mar, Viña del Mar China
Beijing AnZhen Hospital, Capital Medical University, Beijing Cardiovascular Institute and Fu Wai Hospital, Beijing Jilin Province People's Hospital, Changchun The First Hospital of Jilin University, Changchun China-Japan Union Hospital of Jilin University, Changchun Changde Second People's Hospital, Changde Hunan Province People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha The Second Xiangya Hospital Of Central South University, Changsha The Third Hospital of Changsha, Changsha People's Hospital of Sichuan Province, Chengdu Chenzhou No.1 people's Hospital, Chenzhou Second Affiliated Hospital Chongqing Medical University, Chongqing Chongqing Three Gorges Central Hospital, Chongqing Colombia
Cardiomet CEQUIN S.A.S, Armenia Centro de Investigacion Medico Asistencial S.A.S, Barranquilla Corazon IPS S.A.S., Barranquilla Fundacion Santa Fe de Bogota, Bogotá Administradora Country S.A.S., Bogotá Fundacion Hospital Infantil Universitario de San José, Bogotá IPS Centro Medico Julián Coronel S.A., Cali Centro de Diagnostico Cardiologico S.A.S., Cartagena IPS médicos internistas de Caldas S.A.S., Manizales T Y C Inversiones S.A.S Grupsalud, Santa Marta Czechia
MUDr. Hana Burianova, Bílovec Medicus Services Ltd., Brandýs nad Labem Fakultni nemocnice u sv. Anny v Brne, Brno MUDr. Karel Kamenik s.r.o, Brno MUDr. Jan Hubac s.r.o., Chrudim MUDr Petra Maskova PhD, Litovel KardioBusak s.r.o., Louny InterKardioML s.r.o., Mariánské Lázně MUDr. Zdenek Vomacka kardiologie a interna s.r.o., Olomouc MUDr. Jan Kvasnicka CSc, Prague Kardiologie Vinohrady s r o, Prague Institute for Clinical and Experimental Medicine, Prague University Hospital Motol, Prague
Denmark
Sygehus Sønderjylland Åbenrå, Aabenraa Rigshospitalet Copenhagen, Copenhagen Bispebjerg og Frederiksberg Hospital, Copenhagen NV Amager-Hvidovre Hospital, Copenhagen S Herlev and Gentofte Hospital, Herlev Hvidovre Hospital, Hvidovre Sjællands Universitetshospital, Roskilde Slagelse Sygehus, Slagelse Germany
Klinikum am Plattenwald, Bad Friedrichshall Universitätsklinikum Freiburg, Bad Krozingen CIMS Studienzentrum Bamberg GmbH, Bamberg Vivantes Netzwerk für Gesundheit GmbH, Berlin Velocity Clinical Research Germany GmbH, Berlin, Berlin Charité Campus Virchow-Klinikum, Berlin Vivantes Humboldt-Klinikum, Berlin GFO Kliniken Bonn, Betriebsstaette St. Marien, Bonn Universitätsklinikum Bonn AöR, Bonn SANA Kliniken Oberfranken Coburg GmbH, Coburg Klinische Forschung Dresden GmbH, Dresden Facharztzentrum Dresden-Neustadt Betriebsgesellschaft mbH, Dresden Helios Klinikum Erfurt, Erfurt Hungary
Belgyogyaszati es Kardiologiai Maganrendelo, Békéscsaba Budai Irgalmasrendi Korhaz, Budapest Obudai Egeszegugyi Centrum, Budapest Belvaros-Lipotvaros Egeszsegugyi Szolgalat, Budapest Gottsegen National Cardiovascular Center, Budapest Semmelweis University, Budapest Semmelweis University, Budapest Privat Doktor Egeszseguegyi Szolgaltato Zrt., Budapest Zugloi Egeszsegugyi Szolgalat, Budapest Borsod-Abauj-Zemplen Megyei Korhaz es Egyetemi Oktato Korhaz, Miskolc IPR Hungary Kft., Miskolc TaNa Med Kft., Mosonmagyaróvár India
Kamal Nayan Bajaj Hospital, Aurangabad Narayana Institute of Cardiac Sciences, Bangalore S.P. Medical College & Associated Group of Hospitals, Bikaner Tamil Nadu Government Multi Super Speciality Hospital TNGMSSH, Chennai Apollo Hospital - Chennai, Chennai Medanta-The Medicity, Gurgaon IPGMER and SSKM Hospital, Kolkata Supe Heart & Diabetes Hospital & Research Centre, Nashik Chopda Medicare and Research Centre Pvt Ltd, Nashik Max Super Speciality Hospital, New Delhi Indira Gandhi Institute of Medical Sciences, Patna Italy
Humanitas Gavazzeni, Bergamo ASST Papa Giovanni XXIII, Bergamo Az.Osp. Universitaria "Ospedali Riuniti", Foggia Azienda Ospedaliera Universitaria "Federico II", Naples Fondazione IRCCS Policlinico S. Matteo, Pavia Azienda Ospedaliera Universitaria Pisana, Pisa Azienda Ospedaliera Sant'Andrea-Università di Roma La Sapienza, Roma Istituto Clinico Humanitas, Rozzano Japan
Hyogo Prefectural Amagasaki General Medical Center, Amagasaki-shi Asahi General Hospital, Asahi-shi Shonan Fujisawa Tokushukai Hospital, Fujisawa-shi Kyushu University Hospital, Fukuoka Fukuokaken Saiseikai Futsukaichi Hospital, Fukuoka, Chikushino Gunma University Hospital, Gunma, Maebashi Minamino Cardiovascular Hospital, Hachioji-shi National Hospital Organization Hamada Medical Center, Hamada-shi JA-Shizuoka Enshu Hospital, Hamamatsu Hyogo Prefectural Harima-Himeji General Medical Center, Himeji-shi Hiratsuka Kyosai Hospital, Hiratsuka-shi Hitachi Ltd. Hitachinaka General Hospital, Hitachi-Naka National Hospital Organization Kanazawa Medical Center, Ishikawa, Kanazawa
Mexico
Hospital Cardiologica Aguascalientes, Aguascalientes Centro Especializado de Investigación Medical Group Culiacan, Culiacán Centro para el Desarrollo de la Medicina y de Asistencia Medica Especializada S.C., Culiacán Cardiologia Clinica e Intervencionista, Guadalajara Proactive CR Mexico S.A. de C.V., Irapuato Centro de Estudios de Alta Especialidad de Sinaloa CEAES, Mazatlán Clinstile S.A. de C.V., México Cardiolink Clin Trials S.C., Monterrey Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey Centro de Estudios Clinicos de Queretaro S.C, Querétaro Centro de Investigacion Cardiovascular y Metabolica, Tijuana CIMAB S.A. de C.V., Torreón Netherlands
Jeroen Bosch Ziekenhuis-Hertogenbosch, 's-Hertogenbosch Amsterdam University Medical Center, Amsterdam Catharina Ziekenhuis, Eindhoven Universitair Medisch Centrum Groningen, Groningen Maastricht University Medisch Centrum, Maastricht St. Antonius Ziekenhuis, Nieuwegein Isala Klinieken Stichting, Zwolle Poland
Polsko-Amerykanskie Kliniki Serca, Bielsko-Biala Centrum Medyczne Intercor Sp. z o.o., Bydgoszcz Pratia Bydgoszcz Clinical Research Site, Bydgoszcz NZOZ Medical Center KERmed, Bydgoszcz Poradnia Kardiologiczna Jaroslaw Jurowiecki, Gdansk Centrum Medyczne Pratia Gdynia, Gdynia Specjalistyczna Praktyka Lekarska Ewa Mirek-Bryniarska, Krakow Linden Sp. z o.o. sp.k., Krakow Pratia MCM Krakow, Krakow Beata Miklaszewicz & Dariusz Dabrowski Cardiamed Sp. j., Legnica Velocity Nova Sp. z o.o., Lublin Zanamed Medical Clinic Sp. z o.o., Lublin Romania
Spitalul Judetean De Urgenta Dr. Constantin Opris Baia Mare, Baia Mare Spitalul Clinic De Urgenta Prof Dr Agrippa Ionescu, Baloteşti S.C.Centrul Medical Unirea S.R.L., Brasov Spitalul Clinic Judetean de Urgenta Brasov, Brasov Emergency University Hospital, Bucharest Clinica Medicala Data Plus SRL, Bucharest Cluj Napoca Clinical County Hospital, Cluj-Napoca Spitalul Angiocare SRL, Cluj-Napoca Emergency County Hospital Craiova, Craiova Spitalul Clinic Judetean de Urgenta Bihor, Oradea U 2 Serv Com S.R.L., Suceava Country Clinical Emergency Hospital, Targu-Mures, Târgu Mureş Saudi Arabia
King AbdulAziz University Hospital, Al Ahsa King Fahad Specialist Hospital - Research Center, Dammam Imam Abdulrahman bin Faisal University, Dammam King Faisal Specialist Hospital and Research Center, Riyadh King Fahad Medical City, Riyadh Serbia
Clinical Center " Dr Dragisa Misovic Dedinje", Belgrade University Clinical Center of Serbia, Belgrade University Clinical Center of Kragujevac, Kragujevac University Clinical Center Nis, Niš Institute for Treatment and Rehabilitation, Niska Banja, Niška Banja General Hospital Pancevo, Pančevo General Hospital Sveti Luka, Smederevo Institute of Cardiovascular Diseases of Vojvodine, Sremska Mitrovica Health Centre Zajecar, Zaječar Slovakia
Stredoslovensky Ustav Srdcovych A Cievnych Chorob A S, Banská Bystrica Kardiointerna s r o, Banská Bystrica Cliniq s.r.o., Bratislava Premedix Clinic, Bratislava Nemocnica S Poliklinikou Brezno N.O., Brezno Medical Group Kosice s.r.o, Košice Cardio D&R s.r.o. Kosice, Košice Kardiomed s.r.o., Lučenec KVC Kardiovaskularne Centrum s.r.o., Martin Cardiocenter Nitra, s.r.o, Nitra Cardioamb s.r.o, Nové Zámky
South Korea
Inje University Busan Paik Hospital, Busan Dong-A University Hospital, Busan Pusan National University Yangsan Hospital, Busan Chonnam National University Hospital, Gwangju Gachon University Gil Medical Center, Incheon Seoul National University Bundang Hospital, Seongnam Severance Hospital, Seoul Samsung Medical Center, Seoul Korea University Guro Hospital, Seoul Korea University Anam Hospital, Seoul Yonsei University Wonju Severance Christian Hospital, Wŏnju Spain
Hospital Vall Hebron, Barcelona Hospital Clínic de Barcelona, Barcelona Hospital General Universitario Gregorio Marañón, Madrid Hospital Universitario 12 de Octubre, Madrid Hospital Universitario La Paz, Madrid Hospital Universitario Virgen de la Victoria, Málaga Hospital Virgen del Camino, Sanlúcar de Barrameda Hospital Universitario De Torrejon, Torrejón de Ardoz Hospital Clinico Universitario de Valencia, Valencia Hospital General Universitario de Valencia, Valencia Hospital Universitari i Politècnic La Fe, Valencia Hospital Virgen de las Montañas, Villamartín Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung City E-Da Hospital, Kaohsiung City China Medical University Hospital, Taichung Taichung Veterans General Hospital, Taichung Taipei Medical University Hospital, Taipei Taipei Veterans General Hospital, Taipei Tri-Service General Hospital, Taipei Changhua Christian Hospital, Taipei Turkey (Türkiye)
Cukurova Universitesi Tip Fakultesi Gog. Hast. Anabilim Dali, Adana Etlik City Hospital, Ankara Ataturk Universitesi Tip Fakultesi, Erzurum Osmangazi Uni Medical Faculty, Eskişehir Gaziantep University Medical Faculty Sahinbey Educational Research Hospital, Gaziantep Siyami Ersek Heart Hospital, Istanbul Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi, Istanbul Medical Park Pendik Hospital, Istanbul Dokuz Eylul University Faculty of Medicine, Izmir Kutahya Health Science University, Kütahya Inonu Uni. Med. Fac., Battalgazi, Malatya Mersin University Medical Faculty, Mersin United Kingdom
Southmead Hospital, Bristol Golden Jubilee National Hospital, Clydebank Royal Devon and Exeter Hospital, Exeter Calderdale Royal Hospital, Halifax Northwick Park Hospital, Harrow St Bartholomew's Hospital, London Vietnam
Tam Anh General Hospital, Hanoi Hanoi Heart Hospital, Hà Nội Military Hospital 175, Ho Chi Minh City Nguyen Tri Phuong Hospital, Ho Chi Minh City Tam Anh HCMC, Ho Chi Minh City Thong Nhat Hospital HCMC, Ho Chi Minh City Cho Ray Hospital, Ho Chi Minh City Trung Vuong Hospital, Ho Chi Minh City
Key details Sponsor
Boehringer Ingelheim
Enrollment target
~4,200 participants
Primary completion
February 2029
Age range
18 Years and older
Last updated April 2026
Interested in joining? Instituto Médico DAMIC S.R.L., Córdoba
Centro Medico Luquez, Córdoba Centro de Investigaciones Clinicas Baigorria, Granadero Baigorria Hospital Italiano de La Plata, La Plata Centro de Investigaciones Medicas Mar del Plata, Mar del Plata Hospital Universitario Austral, Pilar Instituto Medico CER, Quilmes Instituto de Investigaciones Clínicas de Quilmes, Quilmes DIM Clinica Privada, Ramos Mejía INECO Neurociencias Oroño, Rosario Instituto de Investigaciones Clinicas de Rosario, Rosario Instituto Medico Fundacion Grupo Colaborativo Rosario Investigacion y Prevencion Medica, Rosario Sanatorio Parque S.A., Rosario Investigaciones Clinicas Salta (ICSAL), Salta Centro Cardiovascular Salta, Salta Corporacion Medica de Gral. San Martin S.A., San Martin Investigaciones en Patologias Respiratorias, San Miguel de Tucumán Investigaciones Clinicas Tucuman, San Miguel de Tucumán Centro Integral de Arritmias Tucuman, San Miguel de Tucumán Centro Modelo de Cardiologia, San Miguel de Tucumán Clinica Mayo, San Miguel de Tucumán Instituto de Investigaciones Clinicas San Nicolas, San Nicolás Hospital "Dr. José Maria Cullen", Santa Fe Centro de Investigaciones Clínicas del Litoral, Santa Fe CEMEDIC - Centro de Especialidades Medicas, Villa Luro Via Medica, Goiânia
HC-UFG - Hospital das Clínicas da Universidade Federal de Goiás, Goiânia ICM - Instituto do Coracao de Marilia, Marília Hospital Vera Cruz, Minas Gerais Instituto Atena de Pesquisa Clinica, Natal Instituto Mederi de Pesquisa e Saude, Passo Fundo Hospital de Clínicas de Porto Alegre, Porto Alegre Irmandade da Santa Casa de Misericórdia de Porto Alegre, Porto Alegre Nucleo de Pesquisa Clinica do Rio Grande do Sul (NPCRS), Porto Alegre Hospital Mae de Deus, Porto Alegre Hospital Esperança Recife, Recife Clinicor Clínica Cardiológica LTDA/ Cardio Prime - CAPED, Ribeirão Preto Instituto Brasil de Pesquisa Clinica (IBPClin), Rio de Janeiro Ruschel Medicina e Pesquisa Clínica, Rio de Janeiro Instituto D'Or Pesquisa e Ensino - Rio de Janeiro, Rio de Janeiro Hospital Cardio Pulmonar, Salvador Praxis Pesquisa Medica, Santo André Instituto Domingo Braile, São José do Rio Preto Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto CIPES - Centro Internacional de Pesquisa Clínica, São José dos Campos Cpquali Pesquisa Clinica Ltda, São Paulo CPCLIN - Centro de Pesquisas Clínicas Ltda., São Paulo CEPIC - Centro Paulista de Investigacao Clinica, São Paulo Eurolatino Pesquisas Médicas Ltda., Uberlândia CEDOES - Diagnóstico e Pesquisa,Vitória, Vitória UMHAT "Sv. Georgi", EAD, Plovdiv
UMHAT "Sv. Georgi", EAD, Plovdiv MBAL Sveta Karidad EAD, Plovdiv Medical Center Rusemed EOOD, Rousse National Multiprofile Transport Hospital "Tzar Boris III", Sofia Medical Center For Specialized Medical Help In Cardiovascular Diseases OOD, Sofia University Hospital Lozenetz, Sofia Alexandrovska University Hospital, Sofia Diagnostic Consultative Center Alexandrovska, Sofia University Multidisciplinary Hospital for Active Treatment Sveta Ekaterina EAD, Sofia Medical Center Hera EOOD, Sofia UMHAT "Tsaritsa Yoanna-ISUL" EAD, Sofia ASOMHIDC - Individual practice "Cardio Tonus" EOOD, Sofia Multiprofile Hospital MHATEM 'Pirogov', Sofia, Sofia Diagnostic Consultation Center XX-Sofia EOOD, Sofia Kalimat Medical Center Ltd., Sofia Medical Center Intermedica Ltd., Sofia Medical Center Medicabilis Ltd., Sofia Medical center DEA Medicals Ltd., Sofia Medical Center Zara-Med EOOD, Stara Zagora UMHAT Prof. Dr. Stoyan Kirkovich AD, Stara Zagora MDHAT 'Dr. Stefan Cherkezov', AD, Veliko Tarnovo Medical Center Medica Plus Ltd., Veliko Tarnovo Medical Centre Nevromedics EOOD, Veliko Tarnovo MHAT St Panteleimon, Yambol Institut Universitaire de Cardiologie et de Pneumologie de Quebec (IUCPQ), Québec CIUSSS du Saguenay - Lac-Saint-Jean, Québec CardioVasc HR Inc., Saint-Jean-sur-Richelieu Affiliated Zhongshan Hospital of Dalian University, Dalian Daqingshi People's Hospital, Daqing Deyang People's Hospital, Deyang The First People's Hospital of Foshan, Foshan The First Affiliated Hospital of Fujian Medical University, Fuzhou The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou Guangdong Provincial People's Hospital, Guangzhou Third Affiliated Hospital of Guangzhou Medical University, Guangzhou The Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou Guizhou People's Hospital, Guiyang Hainan General Hospital, Haikou The First Affiliated Hospital of Harbin Medical University, Harbin Jiangmen Central Hospital, Jiangmen Center Hospital of Jinan, Jinan Lanzhou University Second Hospital, Lanzhou Linfen Central Hospital, Linfen Luoyang Third People's Hospital, Luoyang The First Affiliated Hospital of Henan University of Science and Technology, Luoyang Jiangxi Province Integrated Tractional Chinese Medicine& Western Medicine Hospital, Nanchang The First Affiliated Hospital of Nanchang University, Nanchang Zhongda Hospital Southeast University, Nanjing Nanjing Jiangning Hospital, Nanjing The First Affiliated Hospital of Guangxi Medical University, Nanning Nanyang First People's Hospital, Nanyang Nanyang Second General Hospital, Nanyang Ningbo Second Hospital, Ningbo The First Affiliated Hospital of Ningbo University, Ningbo Panjin Liao Oil Gem Flower Hospital, Panjin Pingxiang People's Hospital, Pingxiang Zhongshan Hospital Affiliated to Fudan University, Shanghai Tongren hospital, Shanghai Jiaotong University School of Medicine, Shanghai Shanghai General Hospital, Shanghai Shengjing Hospital of China Medical University, Shenyang People's Hospital of Liaoning Province, Shenyang Shenzhen People's Hospital, Shenzhen The Second Hospital of Hebei Medical University, Shijiazhuang Shanxi Bethune Hospital, Taiyuan Shanxi Cardiovascular Hospital, Taiyuan Taian City Central Hospital, Tai’an Tianjin Union Medical Center Nankai University Affiliated Hospital, Tianjin The 2nd Hospital of Tianjin Medical University, Tianjin Hubei Province Zhongshan Hospital, Wuhan Renmin Hospital of Wuhan University, Wuhan Shaanxi Provincial People's Hospital, Xi'an Xinxiang Central Hospital, Xinxiang The People's Hospital Of Xuancheng City, Xuancheng The General Hospital of XZCMG (The Second Affiliated Hospital of Xuzhou Medical University), Xuzhou The first People's Hosptal of Yinchuan, Yinchuan Yueyang Central Hospital, Yueyang Yuncheng Central Hospital, Yuncheng The First Affiliated Hospital of Hebei North University, Zhangjiakoou The First Affiliated Hospital of Zhengzhou University, Zhengzhou Affiliated Hospital of Jiangsu University, Zhenjiang University Thomayer´s Hospital, Praha 4-Krc
Kardiologicka ambulance MUDr. Ferkl s.r.o., Trutnov Clinical Trials Services s.r.o, Uherské Hradiště Klinische Forschung Hamburg GmbH, Hamburg
Klinische Forschung Hannover-Mitte GmbH, Hanover Medizinische Hochschule Hannover, Hanover Universitätsklinikum Jena, Jena Kardiopraxis Schirmer, Kaiserslautern Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel Asklepios Klinik Langen-Seligenstadt GmbH, Langen Velocity Clinical Research Germany GmbH, Leipzig, Leipzig Klinikum der Stadt Ludwigshafen am Rhein GmbH, Ludwigshafen ze:ro Praxen MVZ fuer Nierenerkrankungen und Bluthochdruck GmbH Mannheim, Mannheim Marienhaus Klinikum St. Elisabeth, Neuwied Kardiologische Praxis Papenburg, Papenburg Universitätsklinikum Regensburg, Regensburg Gemeinschaftspraxis Dr. Josef Grosskopf und Dr. Wilma Grosskopf, Wallerfing Cardiologicum Hamburg GbR, Wandsbek Kardiologische Praxis, Wermsdorf, Wermsdorf Velocity Clinical Research Germany GmbH, Wiesbaden, Wiesbaden Klinikum Worms gGmbH, Worms Coromed-Smo Kft., Pécs
Tolna Varmegyei Balassa Janos Korhaz, Szekszárd Belvarosi Egeszseghaz Kft., Zalaegerszeg Unicare Heart Institute, Surat
King George Hospital, Visakhapatnam National Hospital Organization Iwakuni Clinical Center, Iwakuni-shi
Tokushukai Shonan Kamakura General Hospital, Kamakura-shi Tokushukai Hayama Heart Center, Kanagawa, Miura-gun Mitoyo General Hospital, Kanonji-shi Ibaraki Prefectural Central Hospital, Kasama-shi Kasugai Municipal Hospital, Kasugai-shi Saiseikai Kawaguchi Hospital, Kawaguchi-shi St. Marianna University Hospital, Kawasaki-shi Tokushukai Kishiwada Tokushukai Hospital, Kishiwada-shi National Hospital Organization Kobe Medical Center, Kobe Kumamoto University Hospital, Kumamoto Japanese Red Cross Kumamoto Hospital, Kumamoto National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure Chibanishi General Hospital, Matsudo-shi Shinshu University Hospital, Matsumoto-shi Ehime Prefectural Central Hospital, Matsuyama Matsuyama Shimin Hospital, Matsuyama National Hospital Organization Tokyo Medical Center, Meguro-ku Mito Saiseikai General Hospital, Mito Tohoku University Hospital, Miyagi, Sendai Sendai Cardiovascular Center, Miyagi, Sendai Nagasaki Harbor Medical Center, Nagasaki, Nagasaki Nagoya Kyoritsu Hospital, Nagoya Nagoya City University Hospital, Nagoya Hokushin General Hospital, Nakano-shi Nara Medical University Hospital, Nara, Kashihara Juzenkai The Sakakibara Heart Institute of Okayama, Okayama, Okayama Ome Municipal General Hospital, Ome-shi Nagasaki Medical Center, Omura-shi Osaka Metropolitan University Hospital, Osaka Osaka General Medical Center, Osaka Kosekai Iwatsuki-minami Hospital, Saitama, Saitama Osaka Rosai Hospital, Sakaishi Teine Keijinkai Hospital, Sapporo NHO Sendai Medical Center, Sendai NHO Kanmon Medical Center, Shimonoseki-shi National Cerebral and Cardiovascular Center, Suita-shi The University of Osaka Hospital, Suita-shi Tachikawa Hospital, Tachikawa-shi National Hospital Organization Takasaki General Medical Center, Takasaki-shi NHO Minami Wakayama Medical Center, Tanabe-shi Tokushima Prefectural Central Hospital, Tokushima Tomakomai City Hospital, Tomakomai-shi Toyota Memorial Hospital, Toyota-shi NHO Shinshu Ueda Medical Center, Ueda-shi Yokohama Sakae Kyosai Hospital, Yokohama Nzoz Heureka, Piaseczno
CBK Med Clinic SP Z O O, Płock Centrum Medyczne Medyk, Rzeszów Lukmed Lukasz Wozniak, Siedlce Velocity Skierniewice Sp. z o.o, Skierniewice Centrum Medyczne Pratia Poznan, Skórzewo Velocity Staszow, Staszów Sedimed Sp. z o.o., Szczecin Balsammedica Sp. z o. o., Warsaw MTZ Clinical Research Powered by Pratia, Warsaw 4. Military Clinical Hospital with Polyclinic SP ZOZ, Wroclaw Sedimed Sp. z o.o., Wroclaw Velocity Nova Sp. z o.o., Zamość Centrum Medyczne Serafin med, Żarów Podoleanu G. Cristian-Gheorghe-Calin, Târgu Mureş
Spitalul Clinic Judetean de Urgenta Targu Mures, Târgu Mureş S.C Medicali's S.R.L, Timișoara Timisoara Municipal Emergency Clinical Hospital, Timișoara Nemocnica AGEL Zvolen a.s., Zvolen