Plain-English translation of NCT06937099 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Crohn's Disease research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether combining with another medication called works better than alone for people with moderate to severe Crohn's disease who are also overweight or living with obesity. is a newer medication that helps calm the inflammation in the digestive tract. The study will compare how well the two-medication combination works compared to the single medication, and whether both are safe and well-tolerated.
Many people with Crohn's disease also struggle with weight gain, and existing treatments don't always work well for everyone. Researchers want to see if treating both the inflammation and the weight problem at the same time with two complementary medications could help patients feel better and healthier overall.
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You will receive the first medication through an IV infusion at the start, then switch to injections under the skin along with a second injection (either the second medication or a placebo, depending on which group you're randomly assigned to). The study lasts up to 61 weeks, during which you'll visit the clinic multiple times so doctors can monitor how you're responding, check your symptoms, and watch for any side effects. Blood tests and imaging scans will help track your progress.
AI-generated summary from trial data · Aug 27, 2026 · Not medical advice
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