Plain-English translation of NCT06937996 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This trial is testing the NanoKnife Irreversible Electroporation System, a device that uses electrical pulses to destroy cancer cells, for people with advanced pancreatic cancer that cannot be surgically removed. Researchers want to understand whether this treatment is safe and whether it helps reduce the pain that comes with this type of cancer. The device has been approved by the FDA to treat soft tissue tumors, but this study will be one of the first to formally evaluate how well it works specifically for pancreatic cancer.
Pancreatic cancer that has spread too far to be surgically removed is very difficult to treat, and patients often experience severe pain. This trial exists to see if the electrical ablation approach could offer a new option for people who have limited choices, potentially helping them live more comfortably.
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You would receive the NanoKnife electrical ablation procedure as an outpatient or inpatient treatment. After the procedure, you would have follow-up visits and check-ins at multiple time points — starting at 1 day after treatment and continuing for up to 2 years — where doctors would monitor you for any side effects and ask you to rate your pain and quality of life using standard questionnaires. In total, about 25 patients will participate in this study.
AI-generated summary from trial data · Aug 2, 2026 · Not medical advice
United States
Sponsor
Englewood Hospital and Medical Center
Enrollment target
~25 participants
Started
May 2025
Primary completion
May 2035
Age range
18 Years and older
Last updated on clinicaltrials.gov in June 2025.
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Central contact
Cherif Boutros
Englewood Hospital and Medical Center
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.