Plain-English translation of NCT06939335 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
When someone has a cardiac arrest outside the hospital, paramedics must act quickly to restart their heart and get oxygen to their brain. This trial is testing whether a small adjustment to how paramedics deliver oxygen through a breathing bag—adding what's called positive end-expiratory pressure (PEEP)—can improve survival chances. The study will compare two groups: one receiving this breathing support technique and one receiving standard care.
Cardiac arrest is a life-threatening emergency, and while CPR is essential, doctors aren't sure if the way oxygen is delivered during resuscitation affects survival. Early research suggests this breathing technique might help keep the lungs open and improve blood flow to vital organs, but no major study has tested this yet.
You likely qualify if…
You likely don't qualify if…
If you qualify and are enrolled during a cardiac arrest emergency, paramedics will randomly assign you to receive either standard resuscitation with the new breathing technique or standard resuscitation without it. Sensors will measure the air pressure and flow during your treatment. Your recovery and outcomes—including whether your heart restarts, whether you survive to reach the hospital, and your neurological condition—will be tracked to see if the breathing technique made a difference.
AI-generated summary from trial data · Aug 12, 2026 · Not medical advice
Belgium