Plain-English translation of NCT06940180 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This research study is testing a new combination treatment for advanced sinus and nasal cavity cancers. The study combines a medication called — which helps your immune system fight cancer — with two chemotherapy drugs ( and ) given before surgery to remove the tumor. The goal is to see if this combination can shrink tumors and improve outcomes for people with this type of cancer.
Sinus and nasal cavity cancers are often diagnosed at an advanced stage and are difficult to treat. While this medication has been approved for a similar head and neck cancer in patients who cannot have surgery, it has not yet been tested in combination with chemotherapy before surgery for sinus cancers. This study aims to see if the new treatment approach can help more patients.
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You would receive two 3-week cycles of the new medication combined with chemotherapy through infusions, with imaging scans to monitor how your tumor is responding. After this treatment, you would have surgery to remove your tumor. Depending on what the pathology report shows, you may receive radiation therapy with or without additional chemotherapy after surgery. You would then have follow-up visits every three months for at least one year, including imaging scans to monitor for any recurrence.
AI-generated summary from trial data · Aug 5, 2026 · Not medical advice
United States