Plain-English translation of NCT06940427 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
Researchers are developing a new imaging tool called FAPI PET/MRI that can detect early scarring and damage in the lungs of people with fibrotic lung diseases like hypersensitivity pneumonitis or idiopathic pulmonary fibrosis. Instead of using invasive methods, this scan can show whether scarring is developing or getting worse without needing surgery or biopsies. The goal is to create a better way to monitor lung disease and help doctors decide on treatment more effectively.
Currently, doctors struggle to monitor lung scarring accurately without invasive procedures. This imaging tool could help catch scarring earlier and track how well treatments are working, which would give patients and doctors better information for making treatment decisions.
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You will visit the research center either 2 or 3 times, depending on which group you join and whether your treatment needs change during the study. At each visit, you'll undergo a PET/MRI imaging scan that combines two types of imaging to look for scarring in your lungs; each visit may last up to 2.5 hours. Your regular doctors at UW Health will continue managing your lung disease as part of standard care, and this research fits alongside that care.
AI-generated summary from trial data · Jun 17, 2026 · Not medical advice
United States
Phase
Testing effectiveness
Sponsor
University of Wisconsin, Madison
Enrollment target
~50 participants
Started
November 2025
Primary completion
September 2027
Age range
18 Years and older
Last updated on clinicaltrials.gov in March 2026.
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Central contact
Radiology Studies
University of Wisconsin, Madison
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