Plain-English translation of NCT06943846 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
Researchers are studying whether platelet-rich fibrinogen (PRF)—a substance created from your own blood—can help tooth extraction sites heal better, especially as we age. Some participants will receive this treatment after having a back tooth extracted, while others will not, so the researchers can compare healing between the two groups. The goal is to understand whether this medication works differently in older versus younger people.
After a tooth is extracted, the healing process can take longer in older adults, which may delay getting a dental implant or other replacement. Researchers want to know if this treatment made from a patient's own blood can speed up that healing and whether age affects how well it works.
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On the day of your tooth extraction, you'll have some baseline measurements taken, including a finger-prick blood test and X-rays to plan for a possible future implant. The research team will collect a small sample of fluid from around the teeth next to the one being removed. After your tooth is extracted under local anesthesia, you'll either receive the blood-based treatment or serve as a comparison group that doesn't receive it. The study team will then monitor how well the extraction site heals over time.
AI-generated summary from trial data · Aug 28, 2026 · Not medical advice
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