Plain-English translation of NCT06948058 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing whether e-cigarettes or nicotine replacement therapy (like patches or gum) can help people quit smoking, especially those who also struggle with obesity. Researchers want to understand which approach works better, how well people stick with it, and how it affects their health — including weight, blood sugar, and inflammation. You'd be randomly assigned to try one of these treatments or be in a control group that doesn't receive either product.
Most smoking cessation programs don't focus on people who also have obesity, even though these two conditions often go together and can make quitting harder. This study aims to fill that gap by comparing different nicotine replacement options to see what works best for this specific group of people.
You likely qualify if…
You likely don't qualify if…
If you join, you'll be randomly assigned to one of three groups: one using e-cigarettes, one using nicotine replacement therapy (like patches or gum), or a control group with no product. You'll visit the research team at the start and then have follow-up visits at 1, 2, and 3 months. During these visits, you'll answer questions about your smoking, have your breath tested to confirm smoking status, and provide measurements related to your weight and health. You'll also use your smartphone to help track your progress remotely.
AI-generated summary from trial data · Jun 28, 2026 · Not medical advice
United States
Sponsor
Brown University
Collaborators
National Institute of General Medical Sciences (NIGMS)
Enrollment target
~60 participants
Started
April 2025
Primary completion
May 2027
Age range
21 Years and older
Last updated on clinicaltrials.gov in May 2026.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
CRESCENT Study Research Staff
Brown University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.