Plain-English translation of NCT06951906 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing deep brain stimulation (DBS) surgery—a procedure where doctors implant a device that sends electrical signals to a specific area of the brain—to treat freezing of gait, a symptom of Parkinson's disease where people suddenly feel "stuck" and unable to walk. Researchers will use advanced brain imaging scans before and after surgery to understand which brain structures predict who will benefit most from this treatment, so doctors can eventually personalize the surgery for each patient.
Freezing of gait can be severely disabling for people with Parkinson's disease, and while this treatment works well for some patients, it doesn't help everyone equally. This study aims to identify which patients are most likely to improve and how to better customize the surgery for individual needs.
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If you join this study, you will undergo baseline brain imaging scans and walking assessments before your scheduled deep brain stimulation surgery. After your surgery, you will return for follow-up visits where researchers will repeat the imaging scans and walking tests to see how well the treatment worked and to understand how your brain structure predicted your response. The study follows you over time to connect the imaging findings with your real-world improvement in freezing of gait symptoms.
AI-generated summary from trial data · Aug 21, 2026 · Not medical advice
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