Plain-English translation of NCT06953960 on ClinicalTrials.gov ↗ ·
Phase 1/2 — A combined trial that checks safety and dosing while also starting to look at whether the treatment works.
This trial is testing a new investigational drug called surzetoclax for people with multiple myeloma that has come back or stopped responding to previous treatments. The study will evaluate whether this medication is safe and how well it works, either given on its own or combined with other established myeloma drugs. Researchers want to find the best dose and determine whether the treatment helps slow or control the cancer.
Multiple myeloma is a serious blood cancer that often returns or becomes resistant to standard treatments, leaving patients with limited options. This trial exists to explore whether this medication could offer a new, more effective approach for people whose myeloma has stopped responding to conventional therapies.
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You will take oral tablets of the medication (either alone or combined with injections and other oral medicines, depending on which study group you join) over approximately 4.5 years. You will attend regular visits at a research site for blood tests, medical exams, and monitoring of any side effects to see how well the treatment is working. The trial involves more frequent check-ups and testing than standard myeloma care, so be prepared for a higher treatment burden with regular hospital or clinic appointments.
AI-generated summary from trial data · Jul 18, 2026 · Not medical advice
United States