Plain-English translation of NCT06954610 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This research study is looking at people who have had a stroke despite being on blood-thinning medication for an irregular heartbeat condition called atrial fibrillation. Researchers want to understand why some people still have strokes and identify which patients are at highest risk for another one, so doctors can offer better prevention strategies in the future.
Even with the best blood-thinning medications available, some patients with atrial fibrillation still experience strokes (called breakthrough strokes), and these patients face a very high risk of having another stroke. Current tools doctors use to predict stroke risk don't work well for these high-risk patients, so better ways to identify who needs additional protection are urgently needed.
You likely qualify if…
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As a participant, you would share information about your medical history, heart condition, and the stroke you experienced. Researchers will collect blood samples and other clinical data to look for patterns that help predict stroke risk. You will need to attend follow-up visits at the hospital, though the exact schedule will be explained to you during the study.
AI-generated summary from trial data · Jun 25, 2026 · Not medical advice
Switzerland
Enrollment target
~500 participants
Started
November 2025
Primary completion
June 2028
Age range
18 Years and older
Last updated on clinicaltrials.gov in November 2025.
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Central contact
David Seiffge, Prof. MD
Department of Neurology, Inselspital, University Hospital Bern, Switzerland
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.