Plain-English translation of NCT06958692 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing a medication called to see if it can help treat major depression in adults. Researchers want to know if this medication combination works better than a placebo (a pill with no active ingredient) at reducing depression symptoms. The study will include about 388 people across multiple research centers.
Many people with depression don't get relief from existing antidepressants alone, and doctors need new treatment options. This study explores whether this medication combination could offer a better solution for adults struggling with depression.
You likely qualify if…
You likely don't qualify if…
If you join this trial, you will be randomly assigned to either take the new medication combination or a placebo pill. You won't know which you're receiving — this is what researchers call "blinded." You'll visit the research center multiple times so doctors can check how you're doing, monitor your symptoms, and watch for any side effects. The study will track your depression symptoms using standard rating scales and ask about your overall well-being throughout the trial period.
AI-generated summary from trial data · Jun 2, 2026 · Not medical advice
China