Plain-English translation of NCT06960928 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether sirolimus, a medication that affects how the immune system works, can help people with long COVID feel better. Researchers will compare people who take the medication to people who take a placebo (a pill with no active ingredient) over 12 weeks. The study will measure whether the treatment helps reduce symptoms like fatigue, breathing problems, brain fog, and chest pain.
Long COVID affects millions of people and there are currently no proven treatments specifically for it. This medication has shown promise in early research, and this study aims to find out if it can actually help patients recover and improve their quality of life.
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You would come to Mount Sinai in New York for study visits over 12 weeks. During that time, you would take either the medication or a placebo, starting with a low dose that increases gradually. You would complete questionnaires about your symptoms and how you're feeling, have blood tests, and share information about your health. The study team will track how your symptoms change over time to see if the treatment helps.
AI-generated summary from trial data · Jun 3, 2026 · Not medical advice
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