Plain-English translation of NCT06963268 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Ovarian Neoplasms research guide →Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing the sentinel lymph node technique, a newer surgical approach designed to detect whether cancer has spread to lymph nodes in women with early-stage ovarian cancer. Instead of removing many lymph nodes like traditional surgery does, this technique uses special markers and imaging to identify and remove only the first few lymph nodes where cancer would most likely show up. If this approach works well, it could mean less invasive surgery, faster recovery, and fewer complications for patients.
Standard ovarian cancer surgery removes many pelvic and abdominal lymph nodes to check for cancer spread, which can cause pain, longer hospital stays, and other side effects. This trial exists to see whether the new technique can be just as reliable at finding cancer while causing far less harm to patients.
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If you enroll, during your planned ovarian cancer surgery, your surgeon will inject a small amount of radioactive tracer and a special dye near your ovary and cervix. Using a handheld probe and infrared light, the surgical team will locate the sentinel lymph nodes (the first nodes where cancer would spread) and remove them for detailed examination. After 30 minutes, all identified nodes are collected and analyzed in the lab using advanced techniques to check for any cancer cells. Your participation involves one surgical procedure as part of your standard cancer treatment.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
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