Plain-English translation of NCT06964464 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 4 — The treatment has already been approved. Researchers are tracking how it works in a large number of people over time.
This trial is testing whether works better than — two medications that help the heart work more efficiently — in patients who have a weakened heart and an implanted device called an ICD (a special pacemaker that can deliver life-saving shocks). Right now, you're taking one of these medications, and researchers want to know if switching to the other one might give you better protection against dangerous heart events.
Both medications are used to treat weak hearts and prevent sudden death, but doctors aren't sure which one works better for people who have an ICD implanted. This study aims to find out which medication leads to fewer hospitalizations and dangerous heart rhythm problems.
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You will be randomly assigned to either keep taking your current or switch to at an equal dose. Your doctor will gradually adjust your dose to find the right amount for you. You'll visit the clinic for check-ups and monitoring, and your ICD device will track your heart activity remotely. The study involves 2,000 people at 100 sites across the United States, and researchers will follow how you respond to whichever medication you're taking.
AI-generated summary from trial data · Jul 1, 2026 · Not medical advice
United States