Plain-English translation of NCT06965452 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This study is testing a procedure called trans-arterial embolization using Embozene microspheres to treat chronic pain from facet joint arthritis in the lower spine. The procedure works by blocking the blood supply to the painful joints, similar to techniques already used safely in spine tumor treatment. Researchers want to see if this approach is safe and effective for patients whose pain hasn't improved with standard treatments like injections or physical therapy.
Facet joint arthritis affects most people over 60 and can cause severe, disabling back pain that doesn't respond well to current treatments like steroid injections or nerve blocks. This study exists to find a new option for patients who have exhausted standard pain management approaches before considering surgery.
You likely qualify if…
You likely don't qualify if…
If you qualify, you would undergo a minimally invasive procedure where a radiologist uses imaging to guide a catheter to the small blood vessels supplying your painful facet joints and injects tiny microspheres to block blood flow to those joints. The procedure is done at a single medical center and is similar to angiography procedures commonly performed in hospitals. You would be followed up afterward to monitor your pain relief and watch for any side effects.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States
Sponsor
Northwell Health
Enrollment target
~40 participants
Started
August 2025
Primary completion
August 2026
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 85 Years
Last updated on clinicaltrials.gov in August 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Betsy Moclair
Northwell Health
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.