Plain-English translation of NCT06966206 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 3 — Testing in thousands of people, comparing the treatment against what doctors currently use. This is the last big step before approval.
This trial is testing whether Multiprofen-CC, a medicated cream containing four active ingredients, can help reduce pain and improve hand function in people with hand osteoarthritis. You would apply the medication (or a placebo cream) to your hands three times daily for two weeks, then switch to the other cream for another two weeks. The study aims to see if this treatment is better than a placebo at easing arthritis pain in the hands.
Hand osteoarthritis can make everyday tasks painful and difficult. Researchers want to find out if this topical medication—applied directly to the skin—might be a helpful way to manage pain without requiring pills or injections, especially for people who want to reduce their reliance on pain medications.
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You would visit the clinic three times: once to start, once after 2 weeks, and once after 6 weeks. During the study, you would apply either the medicated cream or a placebo cream to your hands three times each day for 2 weeks, then switch to the other cream for another 2 weeks (without knowing which is which). You would be asked to report any symptoms or side effects you notice, and the researchers would track how your pain, hand function, and overall quality of life change throughout the study.
AI-generated summary from trial data · Jun 24, 2026 · Not medical advice
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