A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting

Phase 3 — Large-scale testing across thousands of people, comparing the new treatment against current standard treatments.

Trial locations(268 sites)

United States

Banner MD Anderson Cancer Center ( Site 0066), Gilbert, Arizona

Mayo Clinic Cancer Center ( Site 0034), Phoenix, Arizona

University of Arizona Cancer Center ( Site 0035), Tucson, Arizona

Roy and Patricia Disney Family Cancer Center ( Site 0055), Burbank, California

Providence Medical Foundation ( Site 0080), Fullerton, California

Hoag Memorial Hospital Presbyterian ( Site 0010), Newport Beach, California

Helios Clinical Research ( Site 0061), Whittier, California

Intermountain Health Cancer Center Saint Joseph ( Site 0062), Denver, Colorado

Intermountain Health St. Mary's Regional Hospital ( Site 0054), Grand Junction, Colorado

AdventHealth Medical Group Oncology and Hematology at Altamonte ( Site 0044), Altamonte Springs, Florida

Florida Cancer Specialists - South ( Site 7004), Fort Myers, Florida

Bioresearch Partner ( Site 0072), Hialeah, Florida

Mayo Clinic Hospital ( Site 0013), Jacksonville, Florida

Florida Cancer Specialists - North ( Site 7002), St. Petersburg, Florida

Fort Wayne Medical Oncology and Hematology ( Site 0084), Fort Wayne, Indiana

Franciscan Health ( Site 0077), Indianapolis, Indiana

Ochsner Clinic Foundation ( Site 0021), New Orleans, Louisiana

Louisiana State University Health Sciences Shreveport ( Site 0053), Shreveport, Louisiana

New England Cancer Specialists ( Site 0051), Westbrook, Maine

Mercy Medical Center - Baltimore ( Site 0015), Baltimore, Maryland

Saint Luke's Cancer Institute ( Site 0059), Kansas City, Missouri

Washington University Siteman Cancer Center ( Site 0031), St Louis, Missouri

Cancer Partners of Nebraska ( Site 0068), Lincoln, Nebraska

Optum Care Cancer Center ( Site 0050), Las Vegas, Nevada

Renown Regional Medical Center ( Site 0041), Reno, Nevada

Hackensack Univ Medical Center (HUMC) ( Site 0007), Hackensack, New Jersey

Rutgers Cancer Institute of New Jersey ( Site 0076), New Brunswick, New Jersey

Altru Health System ( Site 0057), Grand Forks, North Dakota

Good Samaritan Hospital-TriHealth Cancer institute ( Site 0027), Cincinnati, Ohio

Medical University of South Carolina-Hollings Cancer Center ( Site 0016), Charleston, South Carolina

St Francis Cancer Center ( Site 0093), Greenville, South Carolina

Avera McKennan Hospital ( Site 0002), Sioux Falls, South Dakota

Avera Cancer Institute - Yankton ( Site 0089), Yankton, South Dakota

Tennessee Cancer Specialists ( Site 7001), Knoxville, Tennessee

Nashville General Hospital ( Site 0017), Nashville, Tennessee

Vanderbilt-Ingram Cancer Center ( Site 0038), Nashville, Tennessee

Hendrick Medical Center ( Site 0009), Abilene, Texas

JPS Oncology and Infusion Center ( Site 0083), Fort Worth, Texas

Kelsey-Seybold Clinic ( Site 0042), Houston, Texas

Kelsey-Seybold Clinic ( Site 0088), Houston, Texas

Oncology Consultants P.A. ( Site 0073), Houston, Texas

Texas Oncology - San Antonio ( Site 8004), San Antonio, Texas

Intermountain Medical Center ( Site 0074), Murray, Utah

Bon Secours Cancer Institute at St. Francis ( Site 0048), Midlothian, Virginia

Oncology and Hematology Associates of Southwest Virginia (BRCC) ( Site 8005), Roanoke, Virginia

Fred Hutchinson Cancer Center ( Site 0069), Seattle, Washington

Cancer Care Northwest ( Site 0003), Spokane, Washington

Northwest Medical Specialties, PLLC ( Site 0067), Tacoma, Washington

University of Wisconsin-Madison ( Site 0024), Madison, Wisconsin

Argentina

Instituto de Investigaciones Clinicas Mar del Plata ( Site 6008), Mar del Plata, Buenos Aires

Hospital Italiano de Buenos Aires-ginecology ( Site 6003), Buenos Aires, Buenos Aires F.D.

Centro de Educación Médica e Investigaciones clínicas "Dr. Norberto Quirno" (CEMIC) ( Site 6005), Buenos Aires, Buenos Aires F.D.

Fundacion Ars Medica ( Site 6004), San Salvador de Jujuy, Jujuy Province

Sanatorio Parque ( Site 6002), Rosario, Santa Fe Province

Clínica Mayo de Urgencias Médicas Cruz Blanca S.R.L ( Site 6006), San Miguel de Tucumán, Tucumán Province

Sanatorio Finochietto ( Site 6007), Buenos Aires

Sanatorio Allende - Nueva Córdoba ( Site 6000), Córdoba

Sanatorio de la Cañada - Córdoba ( Site 6001), Córdoba

Australia

Chris O'Brien Lifehouse ( Site 1206), Camperdown, New South Wales

Macquarie University ( Site 1203), North Ryde, New South Wales

Monash Health ( Site 1201), Clayton, Victoria

Belgium

Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman ( Site 3204), Liège, Liege

Jessa Ziekenhuis ( Site 3200), Hasselt, Limburg

AZORG Campus Aalst-Moorselbaan ( Site 3201), Aalst, Oost-Vlaanderen

UZ Gent ( Site 3202), Ghent, Oost-Vlaanderen

CHU UCL Namur/Site Sainte Elisabeth ( Site 3203), Namur

Brazil

PRONUTRIR ( Site 6120), Fortaleza, Ceará

Hospital Araújo Jorge ( Site 6100), Goiânia, Goiás

Liga Norte Riograndense Contra o Câncer ( Site 6111), Natal, Rio Grande do Norte

Associação Hospitalar Beneficente São Vicente de Paulo ( Site 6115), Passo Fundo, Rio Grande do Sul

Irmandade da Santa Casa de Misericórdia de Porto Alegre ( Site 6102), Porto Alegre, Rio Grande do Sul

Hospital São Lucas da PUCRS ( Site 6103), Porto Alegre, Rio Grande do Sul

Clínica de Oncologia Reichow ( Site 6112), Blumenau, Santa Catarina

Fundação Pio XII - Hospital de Câncer de Barretos ( Site 6108), Barretos, São Paulo

Hospital de Base de São José do Rio Preto ( Site 6101), São José do Rio Preto, São Paulo

INCA Hospital do Câncer III ( Site 6107), Rio de Janeiro

Canada

NL Health Services ( Site 0232), St. John's, Newfoundland and Labrador

Royal Victoria Regional Health Centre ( Site 0233), Barrie, Ontario

Health Sciences North ( Site 0234), Greater Sudbury, Ontario

Lakeridge Health ( Site 0225), Oshawa, Ontario

The Ottawa Hospital - General Campus-The Ottawa Hospital Cancer Centre ( Site 0209), Ottawa, Ontario

Sault Area Hospital ( Site 0226), Sault Ste. Marie, Ontario

Princess Margaret Cancer Centre ( Site 0208), Toronto, Ontario

Centre Hospitalier de l'Université de Montréal ( Site 0201), Montreal, Quebec

Jewish General Hospital ( Site 0200), Montreal, Quebec

McGill University Health Centre ( Site 0202), Montreal, Quebec

CHU de Quebec Universite Laval - Hopital du Saint-Sacrement ( Site 0203), Québec, Quebec

CIUSSS de l'Estrie-CHUS ( Site 0206), Sherbrooke, Quebec

Chile

Centro de Estudios Clínicos SAGA ( Site 6205), Santiago, Region M. de Santiago

FALP ( Site 6200), Santiago, Region M. de Santiago

Bradfordhill ( Site 6202), Santiago, Region M. de Santiago

ONCOCENTRO APYS ( Site 6204), Viña del Mar, Valparaiso

China

Anhui Provincial Cancer Hospital ( Site 2234), Hefei, Anhui

Beijing Cancer Hospital ( Site 2201), Beijing, Beijing Municipality

The First Affiliated hospital of Xiamen University-Breast Surgery ( Site 2224), Xiamen, Fujian

Guangdong Maternity and Child Health Care Hospital ( Site 2251), Guangzhou, Guangdong

Jiangmen Center Hospital ( Site 2243), Jiangmen, Guangdong

Liuzhou People's Hospital ( Site 2259), Liuchow, Guangxi

Guangxi Medical University Affiliated Tumor Hospital ( Site 2223), Nanning, Guangxi

Harbin Medical University Cancer Hospital ( Site 2204), Haerbin, Heilongjiang

Henan Cancer Hospital ( Site 2238), Zhengzhou, Henan

Wuhan Union Hospital ( Site 2239), Wuhan, Hubei

Renmin Hospital of Wuhan University ( Site 2236), Wuhan, Hubei

Xiangya Hospital of Central South University ( Site 2225), Changsha, Hunan

Colombia

Instituto de Cancerología-Oncology ( Site 6302), Medellín, Antioquia

FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 6311), Bogotá, Bogota D.C.

Clinica Colsanitas S.A, Sede Clínica Universitaria Colombia ( Site 6309), Bogotá, Bogota D.C.

IMAT S.A.S ( Site 6300), Montería, Departamento de Córdoba

Oncologos del Occidente ( Site 6303), Pereira, Risaralda Department

Fundación Valle del Lili ( Site 6308), Cali, Valle del Cauca Department

Czechia

Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 3400), Brno, Brno-mesto

Finland

Oulun yliopistollinen sairaala ( Site 3603), Oulu, North Ostrobothnia

Tampereen ylipistollinen sairaala ( Site 3601), Tampere, Pirkanmaa

Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 3600), Helsinki, Uusimaa

France

Institut Paoli Calmettes. ( Site 3906), Marseille, Bouches-du-Rhone

Centre Georges Francois Leclerc ( Site 3902), Dijon, Bourgogne-Franche-Comté

Centre de Cancerologie du Grand Montpellier ( Site 3910), Montpellier, Herault

Centre Eugène Marquis Rennes - Centre de Lutte Contre le Cancer-Medical Oncology ( Site 3900), Rennes, Ille-et-Vilaine

CHU d'Amiens-Picardie - Hôpital Sud ( Site 3908), Amiens, Somme

HENRI MONDOR HOSPITAL ( Site 3904), Créteil, Val-de-Marne

Institut Curie ( Site 3903), Paris

Germany

InVO Institut für Versorgungsforschung in der Onkologie ( Site 4009), Koblenz, Rhineland-Palatinate

CaritasKlinikum Saarbruecken St. Theresia ( Site 4014), Saarbrücken, Saarland

Helios Klinikum Berlin-Buch ( Site 4008), Berlin

Greece

General Hospital of Athens - Laiko ( Site 4104), Athens, Attica

Aretaieio Hospital Oncology Unit ( Site 4101), Athens, Attica

Metropolitan Hospital ( Site 4102), Athens, Attica

ATHENS MEDICAL CENTER ( Site 4100), Marousi, Attica

European Interbalkan Medical Center ( Site 4103), Thessaloniki

Guatemala

MEDI-K ( Site 6400), Guatemala City

CELAN,S.A ( Site 6401), Guatemala City

INTEGRA Cancer Institute ( Site 6404), Guatemala City

Onco Go, S.A ( Site 6402), Guatemala City

Asociacion Española de Beneficencia ( Site 6403), Guatemala City

Hong Kong

Hong Kong United Oncology Centre ( Site 1304), Jordan

Queen Mary Hospital ( Site 1300), Pokfulam

Prince of Wales Hospital ( Site 1301), Shatin

Tuen Mun Hospital ( Site 1303), Tuenmen

Hungary

Borsod-Abaúj-Zemplén Vármegyei Központi Kórház És Egyetemi Oktatókórház ( Site 4208), Miskolc, Borsod-Abauj Zemplen county

Bacs-Kiskun Varmegyei Oktatokorhaz-Onkoradiologiai Kozpont ( Site 4207), Kecskemét, Bács-Kiskun county

Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ-Onkoterapias Klinika ( Site 4202), Szeged, Csongrád megye

Israel

Rambam Health Care Campus ( Site 4400), Haifa

Meir Medical Center. ( Site 4403), Kfar Saba

Sheba Medical Center ( Site 4401), Ramat Gan

Yitzhak Shamir Medical Center. ( Site 4404), Ẕerifin

Italy

Azienda USL Toscana Nord Ovest_Ospedale Civile di Livorno ( Site 4503), Livorno, Tuscany

Azienda Ospedaliero Universitaria delle Marche ( Site 4509), Ancona

ASST Papa Giovanni XXIII ( Site 4511), Bergamo

Fondazione IRCCS Istituto Nazionale dei Tumori di Milano ( Site 4501), Milan

Azienda Ospedaliero Universitaria Pisana ( Site 4506), Pisa

Istituto Nazionale Tumori Regina Elena ( Site 4512), Roma

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore ( Site 4500), Roma

Japan

Nagoya City University Hospital ( Site 2310), Nagoya, Aichi-ken

National Hospital Organization Shikoku Cancer Center ( Site 2319), Matsuyama, Ehime

National Hospital Organization Hokkaido Cancer Center ( Site 2300), Sapporo, Hokkaido

Kanazawa Medical University Hospital ( Site 2321), Kahoku-gun, Ishikawa-ken

Kanagawa Cancer Center ( Site 2308), Yokohama, Kanagawa

Mie University Hospital ( Site 2312), Tsu, Mie-ken

Naha Nishi Clinic ( Site 2320), Naha, Okinawa

Kansai Medical University Hospital ( Site 2317), Hirakata, Osaka

Kindai University Hospital ( Site 2316), Sakai, Osaka

The University of Osaka Hospital ( Site 2314), Suita, Osaka

Shizuoka Cancer Center ( Site 2309), Sunto-gun, Shizuoka

National Cancer Center Hospital ( Site 2305), Chūō, Tokyo

Malaysia

University Malaya Medical Centre. ( Site 1503), Lembah Pantai, Kuala Lumpur

Hospital Pulau Pinang ( Site 1502), George Town, Pulau Pinang

National Cancer Institute ( Site 1501), Putrajaya, Putrajaya

Sarawak General Hospital ( Site 1504), Kuching, Sarawak

Pantai Hospital Kuala Lumpur ( Site 1500), Kuala Lumpur

New Zealand

Bowen Icon Cancer Centre ( Site 1001), Crofton Downs, Wellington Region

Auckland City Hospital ( Site 1000), Auckland

Norway

Akershus Universitetssykehus ( Site 3701), Lørenskog, Akershus

Drammen Sykehus, Vestre Viken HF ( Site 3700), Drammen, Buskerud

Nordlandssykehuset ( Site 3704), Bodø, Nordland

Stavanger Universitetssjukehus ( Site 3702), Stavanger, Rogaland

Peru

Instituto Regional de Enfermedades Neoplasicas del Centro (IREN CENTRO) ( Site 6605), Concepción, Departamento de Junín

Instituto Regional de Enfermedades Neoplásicas Del Norte ( Site 6606), Trujillo, La Libertad

Hospital Guillermo Almenara Irigoyen ( Site 6601), Lima

IPOR Instituto Peruano de Oncología & Radioterapia ( Site 6600), Lima

Oncosalud ( Site 6603), Lima

Philippines

THE MEDICAL CITY ( Site 1602), Pasig, National Capital Region

Poland

Centrum Onkologii im. Prof. Franciszka Lukaszczyka ( Site 4616), Bydgoszcz, Kuyavian-Pomeranian Voivodeship

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Oddzial w Krakowie ( Site 4612), Krakow, Lesser Poland Voivodeship

Specjalistyczny Szpital im. dra A. Sokolowskiego w Walbrzychu ( Site 4604), Wałbrzych, Lower Silesian Voivodeship

Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie ( Site 4609), Warsaw, Masovian Voivodeship

Bialostockie Centrum Onkologii im.M.Sklodowskiej-Curie ( Site 4608), Bialystok, Podlaskie Voivodeship

Wojewódzki Szpital Specjalistyczny im. J. Korczaka w Słupsku ( Site 4600), Słupsk, Pomeranian Voivodeship

Szpital Kliniczny Ministerstwa Spraw Wewnętrznych i Administracji z Warmińsko-Mazurskim Centrum Onko ( Site 4614), Olsztyn, Warmian-Masurian Voivodeship

Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie ( Site 4611), Koszalin, West Pomeranian Voivodeship

Salve Medica sp. z o.o. sp. k. ( Site 4618), Lodz, Łódź Voivodeship

Swietokrzyskie Centrum Onkologii, Samodzielny Publiczny Zaklad Opieki Zdrowotnej ( Site 4619), Kielce, Świętokrzyskie Voivodeship

Portugal

Unidade Local de Saude Lisboa Ocidental - Hospital de São Francisco Xavier ( Site 4702), Lisbon, Lisbon District

Hospital de Cascais Doutor José de Almeida ( Site 4700), Lisbon

Instituto Portugues de Oncologia do Porto ( Site 4705), Porto

Romania

Spitalul Clinic Filantropia ( Site 4801), Bucharest

Institutul Oncologic Cluj ( Site 4802), Cluj-Napoca

Singapore

National Cancer Centre Singapore ( Site 1700), Singapore, Central Singapore

South Africa

CANCERCARE LANGENHOVEN DRIVE ONCOLOGY CENTRE ( Site 4907), Port Elizabeth, Eastern Cape

Wits Clinical Research ( Site 4903), Johannesburg, Gauteng

LIFE GROENKLOOF-Mary Potter Cancer Centre ( Site 4901), Pretoria, Gauteng

Sandton Oncology Medical Group (Pty) Ltd ( Site 4900), Sandton, Gauteng

Cancercare Rondebosch Oncology ( Site 4906), Cape Town, Western Cape

South Korea

National Cancer Center ( Site 1800), Goyang-si, Kyonggi-do

Seoul National University Bundang Hospital ( Site 1801), Kyonggi-do, Kyonggi-do

Kyungpook National University Chilgok Hospital ( Site 1805), Taegu, Taegu-Kwangyokshi

Seoul National University Hospital ( Site 1806), Seoul

Severance Hospital Yonsei University Health System ( Site 1804), Seoul

Asan Medical Center ( Site 1803), Seoul

Samsung Medical Center ( Site 1807), Seoul

The Catholic University of Korea. Seoul St. Mary s Hospital ( Site 1802), Seoul

Spain

Institut Català d'Oncologia - L'Hospitalet ( Site 5001), L'Hospitalet de Llobregat, Barcelona

Hospital de Basurto ( Site 5007), Bilbao, Bizkaia

Complejo asistencial universitario de Salamanca ( Site 5000), Salamanca, Castille and León

HOSPITAL UNIVERSITARIO DE JAEN ( Site 5003), Jaén, Jaen

CHUS - Hospital Clinico Universitario ( Site 5006), Santiago de Compostela, La Coruna

HOSPITAL UNIVERSITARIO QUIRONSALUD MADRID ( Site 5004), Pozuelo de Alarcón, Madrid

Hospital General de Valencia ( Site 5008), Valencia, Valenciana, Comunitat

Parc de Salut Mar - Hospital del Mar ( Site 5005), Barcelona

Hospital Beata María Ana ( Site 5010), Madrid

Hospital Universitario Virgen Macarena ( Site 5002), Seville

Sweden

Skånes Universitetssjukhus Malmö ( Site 3802), Malmo, Skåne County

Karolinska Universitetssjukhuset Solna ( Site 3800), Stockholm, Stockholm County

Akademiska sjukhuset ( Site 3801), Uppsala, Uppsala County

Södra Älvsborgs Sjukhus Borås ( Site 3804), Borås, Västra Götaland County

Taiwan

Taichung Veterans General Hospital ( Site 1904), Taichung

National Taiwan University Hospital ( Site 1900), Taipei

MacKay Memorial Hospital ( Site 1903), Taipei

National Taiwan University Cancer Center (NTUCC) ( Site 1901), Taipei

Chang Gung Medical Foundation-Linkou Branch ( Site 1906), Taoyuan District

Thailand

Faculty of Medicine Siriraj Hospital ( Site 2000), Bangkok, Bangkok

Chulalongkorn University ( Site 2001), Pathumwan, Bangkok

Songklanagarind Hospital ( Site 2002), Hat Yai, Changwat Songkhla

Maharaj Nakorn Chiang Mai Hospital ( Site 2003), Muang, Chiang Mai

Ukraine

COMMUNAL NONPROFIT ENTERPRISE CLINICAL CENTER OF ONCOLOGY, HEMATOLOGY, TRANSPLANTOLOGY AND PALLIATI ( Site 5207), Cherkasy, Cherkasy Oblast

Municipal Enterprise "Bukovinian сlinical oncology сenter" ( Site 5208), Chernivtsi, Chernivetska Oblast

CNCE Precarpathian Clinical Oncologic Center ( Site 5201), Ivano-Frankivsk, Ivano-Frankivsk Oblast

CNE Regional clinical oncology center of Kirovograd regional Council ( Site 5203), Kropyvnytsky, Kirovohrad Oblast

Shalimov Institute of Surgery and Transplantation ( Site 5210), Kyiv

United Kingdom

Ninewells Hospital and Medical School ( Site 5300), Dundee, Dundee City

Huddersfield Royal Infirmary ( Site 5313), Huddersfield, England

Princess Royal University Hospital ( Site 5316), Orpington, Kent

St Bartholomew s Hospital ( Site 5302), London, London, City of