Plain-English translation of NCT06974617 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
This study doesn't follow the usual testing phases — it may be an observational study or a different type of research.
This trial is testing two different ways to treat chronic migraine — a condition where you have severe headaches on 15 or more days per month. One treatment uses a nasal spray with lidocaine (a numbing medication) applied inside each nostril. The other uses (BOTOX), which is injected at specific points on the head and neck. Researchers want to see which approach works better for people living with chronic migraine.
Chronic migraine can be very disabling, and not all patients respond equally well to existing treatments. By comparing these two different approaches, researchers hope to find the most effective option and give doctors and patients more choices for managing this condition.
You likely qualify if…
You likely don't qualify if…
If you enroll, you will be randomly assigned to receive either the nasal spray treatment or the injection treatment. For the nasal spray group, you will receive 2 milliliters of numbing medication applied inside each nostril. For the injection group, you will receive 100 units of Botox injected at fixed locations on your head and neck. The trial is being conducted at Cairo University, and the research team will monitor how well each treatment reduces your migraine frequency and severity.
AI-generated summary from trial data · Jun 4, 2026 · Not medical advice
Egypt
Sponsor
Cairo University
Enrollment target
~64 participants
Started
May 2025
Primary completion
October 2025
This trial's estimated completion date has passed — the record may not be fully up to date.
Age range
18 Years – 65 Years
Last updated on clinicaltrials.gov in May 2025.
Reach out to the team running this trial. Response times vary — some teams are faster than others.
Central contact
Mohamed E Abdel Fattah, MD
Cairo University
Tell us you're interested and we'll help connect you with the research team. We'll walk you through what to expect first — no email needed to get started.