Plain-English translation of NCT06976853 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This study is testing whether a medication called can help heal the small intestine in people with Crohn's disease whose inflammation hasn't improved with other treatments. Instead of just reducing inflammation like current drugs do, this medication may work differently to actually promote healing of the damaged bowel. Researchers will track how you feel and use colonoscopy, blood tests, and stool samples to see if the medication works.
Some people with Crohn's disease don't respond well enough to existing anti-inflammatory treatments, and their small intestine continues to be damaged. This trial is exploring whether this medication, which works through a different mechanism, might be able to promote actual healing rather than just controlling inflammation.
You likely qualify if…
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You would receive the medication (likely by injection based on how is typically given) and visit the research team regularly so they can monitor how you're doing through questionnaires, blood work, stool samples, and colonoscopies to visualize your bowel. The study will track whether the medication helps heal the damaged areas of your small intestine and gather samples to understand how the treatment works in your body.
AI-generated summary from trial data · Jun 6, 2026 · Not medical advice
United States