A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy — Stella
Phase 2 — Testing in a larger group (up to a few hundred people) to further evaluate safety and begin to assess effectiveness.
(109 sites) United States
Univ of Alabama Birmingham, Birmingham, Alabama TMC Hlthcr Clin Res Office, Tucson, Arizona Pima Heart and Vascular, Tucson, Arizona Valley Clinical Trials, Covina, California UCSD NAFLD Research Center, La Jolla, California Valley Clinical Trials, Northridge, California University of California, San Francisco, San Francisco, California University of California San Francisco UCSF, San Francisco, California Harbor-UCLA Medical Center, Torrance, California CPC Clinical Research & Community Health, Aurora, Colorado Inpatient Research Clinic LLC, Miami Lakes, Florida AdventHealth Orlando, Orlando, Florida Guardian Research Org LLC, Winter Park, Florida UofL Health Care Outpatient, Louisville, Kentucky Henry Ford Hospital_Detroit, Detroit, Michigan University of Minnesota_Minneapolis_1, Minneapolis, Minnesota Washington University School of Medicine, St Louis, Missouri Icahn Sch of Med-Mt Sinai Hosp, New York, New York Duke University, Durham, North Carolina Providence St. Vincent Heart, Portland, Oregon Abington Memorial Hospital, Abington, Pennsylvania Capital Area Research LLC, Camp Hill, Pennsylvania Vanderbilt University Medical Center, Nashville, Tennessee Amarillo Medical Specialists, Amarillo, Texas University of Texas Southwestern Medical Center, Dallas, Texas Texama Medical Center, Denison, Texas East Texas Cardiology PA, Houston, Texas Inova Heart and Vascular Institute, Falls Church, Virginia Sentara Bayside Hospital, Norfolk, Virginia Canada
St Pauls Hospital, Vancouver, British Columbia William Osler Hel Bra Civic Hs, Brampton, Ontario Hamilton Hlth Sc. - General Site, Hamilton, Ontario Hamilton General Hospital, Hamilton, Ontario Cardio Health Clinical Trials, Hamilton, Ontario Cardio Health Clinical Trials, Mississauga, Ontario University of Ottawa Heart Ins, Ottawa, Ontario St. Michael's Hospital, Toronto, Ontario Women's College Hospital, Toronto, Ontario Winchester Dist Memorial Hosp, Winchester, Ontario Unv de Cardiologie et dePneum, Québec Germany
Sana Kliniken Berlin-Brandenburg GmbH - Lichtenberg, Berlin Charité - Campus Benjamin Franklin - Klinik für Kardiologie, Berlin Charité - Campus Virchow-Klinikum - Kardiologie, Angiologie und Intensivmedizin (CRU), Berlin Uniklinik TU Dresden - Herzzentrum Dresden GmbH, Dresden Universitaetsklinikum Essen - Klinik für Kardiologie und Angiologie, Essen Universitätsklinikum Frankfurt aM - Kardiologie, Frankfurt am Main Universitätsklinikum Halle - Innere Medizin III, Halle Medizinische Hochschule Hannover - Kardiologie und Angiologie, Hanover UniklinikHeidelberg - Innere Med. III - Kardiologie, Angiologie, Pneumologie, Heidelberg Uniklinik Schleswig-Holstein - Med. Klinik III Kardiologie und Internist. Intensivmedizin, Kiel India
Rhythm Heart Institute - A unit of Synergy Lifecare Pvt, Vadodara, Gujarat Sengupta Hospital and Research Institute, Nagpur, Maharashtra All India Institute of Medical Sciences (AIIMS), Nagpur, Nagpur, Maharashtra All India Institute of Medical Sciences (AIIMS), Nagpur, Nagpur, Maharashtra G B Pant Institute of Postgraduate Medical Education and Research, New Delhi, National Capital Territory of Delhi VMMC & Safdarjung Hospital, New Dehli, New Delhi VMMC & Safdarjung Hospital, New Dehli, New Delhi Apollo Hospital Chennai, Chennai, Tamil Nadu Apollo Hospital Chennai, Chennai, Tamil Nadu Osmania General Hospital, Hyderabad, Telangana Osmania General Hospital, Hyderabad, Telangana Shri Mahant Indiresh Hospital, Dehradun, Uttarakhand Japan
NIPPON MEDICAL SCHOOL HOSPITAL_Cardiovascular medicine, Bunkyo-ku, Tokyo Hyogo Prefectural HarimaHimeji General Medical Center_Cardiology, Himeji-shi, Hyogo National Hospital Organization Mito Medical Center_Cardiovascular medicine, Ibaraki Yokohama City University Medical Center_Cardiovascular Center, Kanagawa Yokohama City University Medical Center_Cardiovascular Center, Kanagawa Kagawa University Hospital_Cardiology, Kita-gun, Kagawa Kobe City Medical Center General Hospital_Cardiology, Kobe-shi, Hyogo Medical Research Institute KITANO HOSPITAL_Cardiovascular Medicine, Osaka-shi, Osaka Osaka Metropolitan University Hospital_Cardiovascular Medicine, Osaka-Shi, Osaka Sapporo Medical University Hospital_Cardiovascular, Kidney, Metabolism Endocrinology, Sapporo-shi, Hokkaido National Hospital Organization Yokohama Medical Center_Cardiology, Yokohama-shi, Kanagawa Poland
4 Wojskowy Szpital Kliniczny Z Poliklinika Samodzielny Publiczny Zaklad Opieki Zdrowotnej We Wroclawiu, Wroclaw, Lower Silesian Voivodeship 1 Wojskowy Szpital Kliniczny z Poliklinika SPZOZ, Lublin, Lublin Voivodeship Uniwersytecki Szpital Kliniczny w Bialymstoku, Bialystok, Podlaskie Voivodeship American Heart of Poland S.A., Bielsko-Biala Samodzielny Publiczny Zaklad Opieki Zdrowotnej Szpital Uniwersytecki w Krakowie, Krakow Krakowski Szpital Specjalistyczny im. Jana Pawla II, Krakow Szpital Specjalistyczny im. Ludwika Rydygiera w Krakowie Sp. z o.o., Krakow Instytut Centrum Zdrowia Matki Polki, Lodz Uniwersytecki Szpital Kliniczny Nr 4 W Lublinie, Lublin Wojewodzki Szpital Im. Sw.Ojca Pio W Przemyslu, Przemyśl Narodowy Instytut Kardiologii Stefana Kardynala Wyszynskiego Panstwowy Instytut Badawczy, Warsaw Uniwersytecki Szpital Kliniczny Im. Jana Mikulicza-Radeckiego We Wroclawiu, Wroclaw South Korea
Chungbuk National University Hospital, Cheongju-si Keimyung University Dongsan Hospital, Daegu Wonju Severance Christian Hospital, Gangwon-do Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do Korea University Anam Hospital, Seoul Korea University Guro Hospital, Seoul Korea University Guro Hospital, Seoul Spain
Hospital Universitario San Cecilio, Granada, Andalusia Hospital Univ. Virgen de la Arrixaca, El Palmar, Murcia Hospital del Mar, Barcelona Hosp. U Gran Canaria Dr. Negrín_Cardiologia, Las Palmas de Gran Canaria Hospital Ramón y Cajal_Cardiología, Madrid Hospital Universitario La Paz, Madrid Hospital Clinico Universitario de Valencia, Valencia United Kingdom
Trialmed - Midlands, Birmingham Wycombe General Hospital, High Wycombe St Bartholomew's Hospital - Cardiac Research Office, London St Bartholomew's Hospital - Cardiology, London Kings College Hospital, London The Royal Brompton Hospital - Respiratory CRF, London The James Cook University Hospital - Cardiology, Middlesbrough Southampton General Hospital, Southampton
Key details Enrollment target
~200 participants
Primary completion
May 2027
Age range
40 Years – 84 Years
Last updated March 2026
Interested in joining? IPGME&R and SSKM Hospital, Kolkata, West Bengal
Sir Ganga Ram Hospital-Cardiology, New Delhi