Plain-English translation of NCT06991101 on ClinicalTrials.gov ↗ · Source last updated · Translation generated · How we translate trials
Read our Glioblastoma research guide →Phase 2 — Testing in a bigger group (up to a few hundred people) to see if the treatment actually works and is still safe.
This clinical trial is testing a medication called combined with the standard treatment for newly diagnosed glioblastoma (a serious type of brain cancer). Half of the 190 participants will receive along with radiation therapy and chemotherapy (), while the other half will receive just the standard radiation and chemotherapy. Researchers want to see if adding this medication makes the treatment more effective and safe.
Glioblastoma is an aggressive brain cancer, and while radiation and chemotherapy are the current standard treatment, doctors are looking for ways to improve survival and quality of life. This medication may help fight the cancer cells in a new way when combined with existing treatments.
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If you enroll, you'll be randomly assigned to one of two groups — like a coin flip. Both groups receive radiation therapy and chemotherapy; one group also takes the experimental medication. Treatment happens in two phases: during radiation (about 6 weeks) and then a maintenance phase afterward. You'll have regular visits with your care team for blood tests, imaging scans, and check-ups to monitor how you're doing and any side effects.
AI-generated summary from trial data · Jun 7, 2026 · Not medical advice
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